Seminars in Hematology
Volume 47 , Pages S5-S7 , April 2010

Clinical Trials for Human T-Cell Lymphotropic Virus Type I–Associated Peripheral T-Cell Lymphoma in Japan

  • Kensei Tobinai

      Affiliations

    • Corresponding Author InformationAddress correspondence to Kensei Tobinai, MD, PhD, National Cancer Center Hospital, 5-1-1 Tsukiji, Chou-ku, Tokyo, Japan 104-0045

References 

  1. The World Health Organization classification of malignant lymphomas in Japan: incidence of recently recognized entities. Lymphoma Study Group of Japanese Pathologists. Pathol Int. 2000;50:696–702
  2. Shimoyama M. Diagnostic criteria and classification of clinical subtypes of adult T-cell leukaemia-lymphoma (A report from the Lymphoma Study Group (1984-87)). Br J Haematol. 1991;79:428–437
  3. Tsukasaki K, Tobinai K, Shimoyama M, et al. Deoxycoformycin-containing combination chemotherapy for adult T-cell leukemia-lymphoma: Japan Clinical Oncology Group study (JCOG9109). Int J Hematol. 2003;77:164–170
  4. Yamada Y, Tomonaga M, Fukuda H, et al. A new G-CSF-supported combination chemotherapy, LSG15, for adult T-cell leukaemia-lymphoma: Japan Clinical Oncology Group study 9303. Br J Haematol. 2001;113:375–382
  5. Tsukasaki K, Utsunomiya A, Fukuda H, et al. VCAP-AMP-VECP compared with biweekly CHOP for adult T-cell leukemia-lymphoma: Japan Clinical Oncology Group study JCOG9801. J Clin Oncol. 2007;25:5458–5464
  6. Fukushima T, Miyazaki Y, Honda S, et al. Allogeneic hematopoietic stem cell transplantation provides sustained long-term survival for patients with adult T-cell leukemia/lymphoma. Leukemia. 2005;19:829–834
  7. Ishida T, Utsunomiya A, Iida S, et al. Clinical significance of CCR4 expression in adult T-cell leukemia/lymphoma: its close association with skin involvement and unfavorable outcome. Clin Cancer Res. 2003;9:3625–3634
  8. Yamamoto K, Tobinai K, Utsunomiya A, et al. Phase I study of KW-0761, a defucosylated anti-CCR4 antibody, in relapsed patients (pts) with adult T-cell leukemia-lymphoma (ATL) or peripheral T-cell lymphoma (PTCL): updated results [abstr 1007]. Blood. 2008;112:370
  9. Querfeld C, Kuzel TM, Guitart J, Rosen ST. Preliminary results of a phase II study of CC-5013 (lenalidomide, Revlimid) in patients with cutaneous T-cell lymphoma [abstr 3351]. Blood. 2005;106:936a

 STATEMENT OF CONFLICT OF INTEREST: Dr Tobinai has no conflicts of interest to disclose.

PII: S0037-1963(10)00016-8

doi: 10.1053/j.seminhematol.2010.01.015

Seminars in Hematology
Volume 47 , Pages S5-S7 , April 2010

Article Tools