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Seminars in Hematology
Volume 47
, Pages S11-S14
, April 2010
Novel Agents in Development for Peripheral T-Cell Lymphoma
References
- Phase II-I-II study of two different doses and schedules of pralatrexate, a high-affinity substrate for the reduced folate carrier, in patients with relapsed or refractory lymphoma reveals marked activity in T-cell malignancies. J Clin Oncol. 2009;27:4357–4364
- . ODAC briefing document—Pralatrexate injection (US Food and Drug Administration, 2009). http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/OncologicDrugsAdvisoryCommittee/UCM180636.pdfAccessed January 11, 2010
- Phase IIb multicenter trial of vorinostat in patients with persistent, progressive, or treatment refractory cutaneous T-cell lymphoma. J Clin Oncol. 2007;25:3109–3115
- Results of a phase 2 NCI multicenter study of romidepsin in patients with relapsed peripheral T-cell lymphoma (PTCL) [abstr 1567]. Blood. 2008;112:555
- The schedule-dependent effects of the novel antifolate pralatrexate and gemcitabine are superior to methotrexate and cytarabine in models of human non-Hodgkin's lymphoma. Clin Cancer Res. 2006;12:924–932
- Therapy with gemcitabine in pretreated peripheral T-cell lymphoma patients. Ann Oncol. 1998;9:1351–1353
- . Treatment of refractory T-cell malignancies using gemcitabine. Br J Haematol. 2001;113:185–187
- Pralatrexate and gemcitabine in patients with relapsed or refractory lymphoproliferative malignancies: phase I results [abstr 1674]. Blood. 2009;114:667
- Phase II trial of proteasome inhibitor bortezomib in patients with relapsed or refractory cutaneous T-cell lymphoma. J Clin Oncol. 2007;25:4293–4297
- Phase I study of proteasome inhibitor bortezomib plus CHOP in patients with advanced, aggressive T-cell or NK/T-cell lymphoma. Ann Oncol. 2008;19:2079–2083
- . Evaluation of the potential of histone deacetylase inhibitors to synergize the antineoplastic effects of the proteasome inhibitor bortezomib in mantle cell lymphoma (MCL) [abstr 8584]. J Clin Oncol. 2009;27:454s
- ABT-263 activity and safety in patients with relapsed or refractory lymphoid malignancies in particular chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) [abstr 8574]. J Clin Oncol. 2009;27:452s
- Phase 1 study of ABT-263, a Bcl-2 family inhibitor, in relapsed or refractory lymphoid malignancies [abstr 2108]. Blood. 2008;112:734
- The BH3-only mimetic ABT-737 synergizes the antineoplastic activity of proteasome inhibitors in lymphoid malignancies. Blood. 2008;112:2906–2916
- Activity of lenalidomide in a phase II trial for T-cell lymphoma: report on the first 24 cases [abstr 8524]. J Clin Oncol. 2009;27:439s
- . [Purine nucleoside phosphorylase (PNP) deficiency]. Nippon Rinsho. 1996;54:3328–3332
- . Forodesine IV (Bcx-1777) is clinically active in relapsed/refractory T-cell leukemia: results of a phase II study (interim report) [abstr 1851]. Blood. 2006;108:524a
- . Deoxycoformycin in the treatment of mature T-cell leukaemias. Br J Cancer. 1991;64:903–906
- . Treatment of refractory T-cell malignancies using gemcitabine. Br J Haematol. 2001;113:185–187
- . A pilot study of alemtuzumab (anti-CD52 monoclonal antibody) therapy for patients with relapsed or chemotherapy-refractory peripheral T-cell lymphomas. Blood. 2004;103:2920–2924
- . Phase II study of pentostatin in advanced T-cell lymphoid malignancies: update of an M.D. Anderson Cancer Center series. Cancer. 2004;100:342–349
- . Phase II trial of denileukin diftitox for relapsed/refractory T-cell non-Hodgkin lymphoma. Br J Haematol. 2007;136:439–447
- First report of a phase II clinical trial of lenalidomide oral therapy for peripheral T-cell lymphoma. Blood. 2007;110:Abstract 2579
- Results of a phase II study of 506U78 in cutaneous T-cell lymphoma and peripheral T-cell lymphoma: CALGB 59901. Leuk Lymphoma. 2007;48:97–103
STATEMENT OF CONFLICT OF INTEREST: Dr O'Connor discloses the following relationships: Contracted Research: Allos, Millennium, Abbott, Lily.
PII: S0037-1963(10)00015-6
doi: 10.1053/j.seminhematol.2010.01.014
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Seminars in Hematology
Volume 47
, Pages S11-S14
, April 2010
