Seminars in Hematology
Volume 47 , Pages S1-S4 , April 2010

Functional Classification of Peripheral T-Cell Lymphomas as an Approach to Improve Outcome Prediction and Therapy Selection

  • Dan Jones

      Affiliations

    • Corresponding Author InformationAddress correspondence to Dan Jones, MD, PhD, Professor, Hematopathology, 1515 Holcombe Blvd, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030

References 

  1. WHO classification of tumours of haematopoietic and lymphoid tissues. Lyon, France: IARC Press; 2008;
  2. Vose J, Armitage J, Weisenburger D. International peripheral T-cell and natural killer/T-cell lymphoma study: pathology findings and clinical outcomes. J Clin Oncol. 2008;26:4124–4130
  3. Savage KJ. Prognosis and primary therapy in peripheral T-cell lymphomas. Hematology Am Soc Hematol Educ Program. 2008;280–288
  4. Herling M, Khoury JD, Washington LT, Duvic M, Keating MJ, Jones D. A systematic approach to diagnosis of mature T-cell leukemias reveals heterogeneity among WHO categories. Blood. 2004;104:328–335
  5. Lee Y, Uhm JE, Lee HY, et al. Clinical features and prognostic factors of patients with “peripheral T cell lymphoma, unspecified”. Ann Hematol. 2009;88:111–119
  6. Rodriguez J, Conde E, Gutierrez A, et al. The adjusted International Prognostic Index and beta-2-microglobulin predict the outcome after autologous stem cell transplantation in relapsing/refractory peripheral T-cell lymphoma. Haematologica. 2007;92:1067–1074
  7. Sonnen R, Schmidt WP, Muller-Hermelink HK, Schmitz N. The International Prognostic Index determines the outcome of patients with nodal mature T-cell lymphomas. Br J Haematol. 2005;129:366–372
  8. Gallamini A, Stelitano C, Calvi R, et al. Peripheral T-cell lymphoma unspecified (PTCL-U): a new prognostic model from a retrospective multicentric clinical study. Blood. 2004;103:2474–2479
  9. Croce CM. Role of TCL1 and ALL1 in human leukemias and development. Cancer Res. 1999;59:1778s–1783s
  10. Herling M, Patel KA, Teitell MA, et al. High TCL1 expression and intact T-cell receptor signaling define a hyperproliferative subset of T-cell prolymphocytic leukemia. Blood. 2008;111:328–337
  11. Amin HM, Lai R. Pathobiology of ALK+ anaplastic large-cell lymphoma. Blood. 2007;110:2259–2267
  12. Rassidakis GZ, Thomaides A, Atwell C, et al. JunB expression is a common feature of CD30+ lymphomas and lymphomatoid papulosis. Mod Pathol. 2005;18:1365–1370
  13. Feldman AL, Law M, Remstein ED, et al. Recurrent translocations involving the IRF4 oncogene locus in peripheral T-cell lymphomas. Leukemia. 2009;23:574–580

 STATEMENT OF CONFLICT OF INTEREST: Dr Jones has no conflicts of interest to disclose.

PII: S0037-1963(10)00014-4

doi: 10.1053/j.seminhematol.2010.01.013

Seminars in Hematology
Volume 47 , Pages S1-S4 , April 2010

Article Tools