Seminars in Hematology
Volume 47, Issue 1 , Pages 46-50 , January 2010

Transplant Outcomes in Acute Leukemia (I)

  • Mary Eapen

      Affiliations

    • Statistical Center, Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, WI
    • Corresponding Author InformationAddress correspondence to Mary Eapen, MD, Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee WI 53226
    • ,
  • John E. Wagner

      Affiliations

    • Division of Pediatric Hematology, Oncology and Transplantation, Department of Pediatrics and the Blood and Marrow Transplant Program, University of Minnesota, Minneapolis, MN

References 

  1. Lee SJ, Klein J, Haagenson M, Baxter-Lowe L, Confer DL, Eapen M, et al. High resolution donor-recipient HLA matching contributes to the success of unrelated donor transplantation. Blood. 2007;110:4576–4583
  2. Woolfrey A, Klein J, Haagenson M, Spellman SR, Battiwalla M, Gajewski J, et al. Evaluation of human leukocyte antigen matching requirements for unrelated donor peripheral blood stem cell transplant [abstract]. ASH Annual Meeting Abstracts. 2008;112:563
  3. Rocha V, Cornish J, Sievers EL, Filipovich A, Locatelli F, Peters C, et al. Comparison of outcomes of unrelated bone marrow and umbilical cord blood transplants in children with acute leukemia. Blood. 2001;97:2962–2971
  4. Eapen M, Rubinstein P, Zhang M-J, Stevens C, Kutrzburg J, Scaradavou A, et al. Outcomes of transplantation of unrelated donor umbilical cord blood and bone marrow in children with acute leukemia: a comparison study. Lancet. 2007;369:1947–1954
  5. Wagner JE, Barker JN, DeFor TE, Baker KS, Blazar BR, Eide C, et al. Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and non-malignant diseases: influence of CD34 cell dose and HLA disaprity on treatment-related mortality and survival. Blood. 2002;100:1611–1618
  6. van Heeckeren WJ, Fanning LR, Meyerson HJ, Fu P, Lazarus HM, Cooper BW, et al. Influence of human leukocyte antigen disparity and graft lymphocytes on allogeneic engraftment and survival after umbilical cord blood transplant in adults. B J Haematol. 2007;139:464–474
  7. Laughlin MJ, Eapen M, Rubinstein P, Wagner JE, Zhang M-J, Champlin RE, et al. Outcomes after transplantation of cord blood or bone marrow from unrelated donors in adults with leukemia. N Engl J Med. 2004;351:2265–2275
  8. Rocha V, Labopin M, Sanz G, Arcese W, Schwerdtfeger R, Bosi A, et al. Transplantation of umbilical cord blood or bone marrow from unrelated donors in adults with acute leukemia. N Engl J Med. 2004;351:2276–2285
  9. Gluckman E, Rocha V. Donor selection for unrelated cord blood transplants. Curr Opin Immunol. 2006;18:565–570
  10. Atsuta Y, Suzuki R, Nagamura-Inoue T, Taniguchi S, Takahashi S, Kai S, et al. Disease specific analysis of unrelated cord blood transplantation compared with unrelated bone marrow transplantation in adult patients with acute leukemia. Blood. 2009;113:1631–1637
  11. Oh H, Loberiza FR, Zhang M-J, Ringden O, Akiyama H, Asai T, et al. Comparison of graft-versus-host disease and survival after HLA-identical sibling bone marrow transplantation in ethnic populations. Blood. 2005;105:1408–1416
  12. Barker JN, Wesidorf DJ, DeFor TE, Blazar BR, McGlave PB, Miller JS, et al. Transplantation of 2 partially HLA-matched umbilical cord blood units to enhance engraftmnet in adults with hematological malignancy. Blood. 2005;105:1343–1347
  13. Brunstein CG, Barker JN, Wesidorf DW, DeForr TE, Miller JS, Blazar B, et al. Umbilical cord blood transplantation after nonmyeloablative conditioning: impact on transplantation outcomes in 110 adults with hematologic disease. Blood. 2007;110:3064–3070
  14. Robinson SN, Ng J, Niu T, Yang H, McMannia JD, Karandish S, et al. Superior ex-vivo cord blood expansion following co-culture with bone marrow derived mesenchymal stem cells. Bone Marrow Transplant. 2006;37:359–366
  15. Bautista G, Cabrera JR, Regidor C, Fores R, Gracia-Marco JA, Ojeda E, et al. Cord blood transplants supported by co-infusion of mobilized hematopoietic stem cells from a third party donor. Bone Marrow Transplant. 2009;43:365–373
  16. Jaroscak J, Goltry K, Smith A, Walters-Pick B, Martin PL, Driscoll TA, et al. Augmentation of umbilical cord blood (UCB) transplantation with ex-vivo expanded UCB cells: results of a phase I trial using the Asstrom Replicell System. Blood. 2003;101:5061–5067
  17. Eapen M, Logan BR, Confer DL, Haagenson M, Wagner JE, Weisdorf DJ, et al. Peripheral blood grafts from unrelated donors are associated with increased acute and chronic graft-versus-host disease without improved survival. Biol Blood Marrow Transplant. 2007;13:1461–1468
  18. Schmitz N, Eapen M, Horowitz MM, Zhang M-J, Klein JP, Rizzo JD, et al. Long-term outcome of patients transplanted with mobilized blood or bone marrow: a report from the International Bone Marrow Transplant Registry and the European Group for Blood and Marrow Transplantation. Blood. 2006;108:4288–4290

PII: S0037-1963(09)00138-3

doi: 10.1053/j.seminhematol.2009.10.007

Seminars in Hematology
Volume 47, Issue 1 , Pages 46-50 , January 2010

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