Seminars in Hematology
Volume 47, Issue 1 , Pages 97-103, January 2010

Umbilical Cord Transplantation: Epilogue

  • Hal E. Broxmeyer

      Affiliations

    • Corresponding Author InformationAddress correspondence to Hal E. Broxmeyer, PhD, Department of Microbiology and Immunology, Indiana University School of Medicine, 950 W Walnut St, R2 Building, Room 302, Indianapolis, IN 46202-5181

Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN

The field of cord blood transplantation has come a long way since the first transplant more than 20 years ago. Advancements in the field will require continuing efforts to better understand hematopoietic stem and progenitor cell function and engraftment. Cautious optimism is inherent in the potential relevance and applicability of nonhematopoietic stem and progenitor cell types found in cord blood, and induced pluripotent stem cells generated from cord blood cells. Rigorous investigations and close interactions between scientific and clinical investigators are required to translate human in vitro and animal in vivo findings into clinical utility.

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 Some studies referred to in this article from the author's laboratory were supported by US Public Service Health Awards No. R01HL5646 and R01HL67384, and a Project in P01HL67384 from the National Institutes of Health to H.E.B.

PII: S0037-1963(09)00133-4

doi:10.1053/j.seminhematol.2009.10.002

Seminars in Hematology
Volume 47, Issue 1 , Pages 97-103, January 2010

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