Seminars in Hematology
Volume 46, Issue 1 , Pages 89-99, January 2009

Immunotherapy in Acute Leukemia

  • Wing Leung

      Affiliations

    • Corresponding Author InformationAddress correspondence to Wing Leung, MD, PhD, Department of Oncology, Mail Stop 260, St. Jude Children's Research Hospital, 262, Danny Thomas Place, Memphis, TN 38105

Division of Bone Marrow Transplantation and Cellular Therapy, Department of Oncology, St. Jude Children's Research Hospital; and Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN

Recent advances in immunotherapy of cancer may represent a successful example in translational research, in which progress in knowledge and technology in immunology has led to new strategies of immunotherapy, and even past failures in many clinical trials have led to a better understanding of basic cancer immunobiology. This article reviews the latest concepts in antitumor immunology and its application in the treatment of cancer, with particular focus on acute leukemia.

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 Supported in part by National Institutes of Health Grant No. P30CA21765-24, the Assisi Foundation of Memphis, and the American Lebanese Syrian Associated Charities (ALSAC).

PII: S0037-1963(08)00147-9

doi:10.1053/j.seminhematol.2008.09.004

Seminars in Hematology
Volume 46, Issue 1 , Pages 89-99, January 2009

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