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Seminars in Hematology
Volume 45
, Pages S16-S20
, April 2008
Platelet Tissue Factor: How Did It Get There and Is It Important?
References
- . Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse. Nat Med. 2002;8:1175–1181
- . Platelet deposition inhibits tissue factor activity: In vitro clots are impermeable to factor Xa. Blood. 2004;104:123–127
- . Tissue factor: In at the start … and the finish?. J Thromb Haemost. 2003;1:878–880
- . Leukocyte-versus microparticle-mediated tissue factor transfer during arteriolar thrombus development. J Leukoc Biol. 2005;78:1318–1326
- Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall. Blood. 2005;105:192–198
- . Hematopoietic cell-derived microparticle tissue factor contributes to fibrin formation during thrombus propagation. Blood. 2004;104:3190–3197
- Blood-borne tissue factor: Another view of thrombosis. Proc Natl Acad Sci USA. 1999;96:2311–2315
- . Platelets, circulating tissue factor, and fibrin colocalize in ex vivo thrombi: Real-time fluorescence images of thrombus formation and propagation under defined flow conditions. Blood. 2002;100:2787–2792
- Transfer of tissue factor from leukocytes to platelets is mediated by CD15 and tissue factor. Blood. 2000;96:170–175
- Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-alpha production in vivo. Blood. 2006;107:637–641
- . Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation. Blood. 2005;106:1604–1611
- Accumulation of tissue factor into developing thrombi in vivo is dependent upon microparticle P-selectin glycoprotein ligand 1 and platelet P-selectin. J Exp Med. 2003;197:1585–1598
- Time course of tissue factor procoagulant activity increases on mononuclear cells and platelets following endotoxin-induced systemic inflammation in humans. Blood. 2003;102:551a;(abstr)
- . Generation of tissue factor-rich microparticles in an ex vivo whole blood model. Blood Coagul Fibrinolysis. 2005;16:399–405
- . Granulocytes do not express but acquire monocyte-derived tissue factor in whole blood: Evidence for a direct transfer. Blood. 2008;111:1208–1216
- Human polymorphonuclear leukocytes produce and express functional tissue factor upon stimulation. J Thromb Haemost. 2006;4:1323–1330
- . Induction of tissue factor expression in whole blood: Lack of evidence for the presence of tissue factor expression in granulocytes. Thromb Haemost. 2000;83:861–867
- Platelet-associated tissue factor contributes to the collagen-triggered activation of blood coagulation. Biochem Biophys Res Commun. 2001;281:603–609
- Platelet ADP receptors contribute to the initiation of intravascular coagulation. Blood. 2004;103:594–600
- . Initiation of coagulation by tissue factor carriers in blood. Blood Cells Mol Dis. 2006;36:188–190
- . Granulocytes enhance LPS-induced tissue factor activity in monocytes via an interaction with platelets. J Leukoc Biol. 1993;54:275–282
- . The role of platelets in decrypting monocyte tissue factor. Dis Mon. 2003;49:7–13
- Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets. FASEB J. 2003;17:476–478
- . Tissue factor-enriched vesicles are taken up by platelets and induce platelet aggregation in the presence of factor VIIa. Thromb Haemost. 2007;97:202–211
- Platelet activation induces cell-surface immunoreactive tissue factor expression, which is modulated differently by antiplatelet drugs. Arterioscler Thromb Vasc. 2003;23:1690–1696
- . Human platelets synthesize and express functional tissue factor. Blood. 2007;109:5242–5250
- Escaping the nuclear confines: signal-dependent pre-mRNA splicing in anucleate platelets. Cell. 2005;122:379–391
- Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenicity of human platelets. J Exp Med. 2006;203:2433–2440
- . Active tissue factor in blood?. Nat Med. 2004;10:1155–1156
- . Tissue factor activity in whole blood. Blood. 2005;105:2764–2770
- . Factor VIIa-mediated tenase function on activated platelets under flow. J Thromb Haemost. 2004;2:1402–1410
- . Up against the wall. Blood. 2005;106:1505
- . Mature tissue factor mRNA is expressed in vivo by platelets isolated from patients with sepsis. Chest. 2006;130:134S;(abstr)
- Inhibition of tissue factor limits the growth of venous thrombus in the rabbit. J Thromb Haemost. 2003;1:889–895
- . Recombinant human factor VIIa (rFVIIa) can activate factor FIX on activated platelets. J Thromb Haemost. 2004;2:1816–1822
- . Platelet activity of high-dose factor VIIa is independent of tissue factor. Br J Haematol. 1997;99:542–547
- Stored platelets contain residual amounts of tissue factor: Evidence from studies on platelet concentrates stored for prolonged periods. Transfusion. 2005;45:572–579
- . Role of the extrinsic pathway of blood coagulation in hemostasis and thrombosis. Arterioscler Thromb Vasc Biol. 2007;27:1687–1693
STATEMENT OF CONFLICT OF INTEREST: Nigel Key has received research grants from Novo Nordisk, and has served on advisory boards for Novo Nordisk and Baxter.
PII: S0037-1963(08)00052-8
doi: 10.1053/j.seminhematol.2008.03.012
© 2008 Elsevier Inc. All rights reserved.
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Seminars in Hematology
Volume 45
, Pages S16-S20
, April 2008
