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Seminars in Hematology
Volume 44, Issue 4
, Pages 286-295
, October 2007
High-Dose Chemotherapy With Autologous Hematopoietic Stem Cell Support for Solid Tumors in Adults
References
- . Dose intensity versus total dose of chemotherapy: An experimental basis. In: De Vita VT, Hellman S, Rosenberg SA editor. Important Advances in Oncology. Philadelphia, PA: Lippincott; 1990;p. 43–64
- Autologous hematopoietic stem cell transplantation for breast cancer in Europe: Critical evaluation of data from the European Group for Blood and Marrow Transplantation (EBMT) Registry 1990-1999. Bone Marrow Transplant. 2003;32:489–494
- High-dose combination alkylating agent chemotherapy with autologous bone marrow support for metastatic breast cancer. J Clin Oncol. 1986;4:1592–1597
- High-dose chemotherapy and autologous bone marrow support as consolidation after standard-dose adjuvant therapy for high-risk primary breast cancer. J Clin Oncol. 1993;11:1132–1143
- Efficacy, toxicity, and applicability of high-dose sequential chemotherapy as adjuvant treatment in operable breast cancer with 10 or more involved axillary nodes: Five-year results. J Clin Oncol. 1997;15:2312–2321
- . Therapeutic relevance of CD34 cell dose in blood cell transplantation for cancer therapy. J Clin Oncol. 2000;18:1360–1377
- High-dose chemotherapy for high-risk primary breast cancer: An on-site review of the Bezwoda study. Lancet. 2000;355:999–1003
- . Haematopoietic stem cell transplantation (HSCT) in Europe 2002 (Changes in indication and impact of team density. A report of the EBMT activity survey). Bone Marrow Transplant. 2004;34:855–875
- Randomized trial of high-dose chemotherapy and autologous hematopoietic stem cell support for high-risk primary breast carcinoma: Follow-up at 12 years. Cancer. 2006;106:2327–2336
- Randomized trial of high-dose chemotherapy and hematopoietic progenitor-cell support in operable breast cancer with extensive lymph node involvement: Final analysis with 7 years of follow-up. Ann Oncol. 2002;13:689–698
- Randomized phase 3 study of high-dose chemotherapy (HDC) with autologous stem cell support as consolidation in high-risk postoperative breast cancer: Japan Clinical Oncology (JCOG9208). Proc Am Soc Clin Oncol. 2001;20:38a;(abstr)
- Tailored fluorouracil, epirubicin and cyclophosphamide compared with marrow-supported high-dose chemotherapy as adjuvant treatment for high-risk breast cancer: A randomized trial (Scandinavian Breast Group 9401 study). Lancet. 2000;356:1384–1391
- Conventional adjuvant chemotherapy versus single-cycle, autograft-supported, high-dose, late-intensification chemotherapy in high-risk breast cancer patients: A randomized trial. J Natl Cancer Inst. 2004;96:1076–1083
- High-dose chemotherapy with autologous hematopoietic stem-cell support compared with standard-dose chemotherapy in breast cancer patients with 10 or more positive lymph nodes: First results of a randomized trial. J Clin Oncol. 2004;22:2273–2283
- High dose chemotherapy and autologous stem cell transplantation as adjuvant therapy for primary breast cancer patients with four or more lymph nodes involved: Long-term results of an international randomised trial. Ann Oncol. 2005;16:726–734
- Conventional adjuvant chemotherapy with or without high-dose chemotherapy and autologous stem cell transplantation in high risk breast cancer. N Engl J Med. 2003;349:17–26
- . Stem-cell transplantation for high-risk breast cancer. N Engl J Med. 2003;349:80–82
- Prospective, randomized comparison of high-dose chemotherapy with stem-cell support versus intermediate-dose chemotherapy after surgery and adjuvant chemotherapy in women with high-risk primary breast cancer: A report of CALGB 9082, SWOG 9114, and NCIC MA-13. J Clin Oncol. 2005;23:2191–2200
- A prospective, randomized comparison of two doses of combination alkylating agents (AA) as consolidation after CAF in high-risk primary breast cancer involving ten or more axillary lymph nodes (LN): Preliminary results of CALGB 9082/SWOG 9114/NCIC MA-13. Proc Am Soc Clin Oncol. 1999;18:1a;(abstr)
- Adjuvant high-dose improves early outcome for high-risk (N>7) breast cancer patients: The PEGASE-01 trial. Proc Am Soc Clin Oncol. 2001;20:26a;(abstr)
- . Five-year results of the randomized clinical trial comparing standard versus high-dose myeloablative chemotherapy in the adjuvant treatment of breast cancer with >3 positive nodes (LN+). Proc Am Soc Clin Oncol. 2001;20:21a;(abstr)
- Multicycle dose-intensive chemotherapy for women with high-risk primary breast cancer: Results of International Breast Cancer Study Group Trial 15-95. J Clin Oncol. 2006;24:370–378
- Efficacy of high-dose alkylating chemotherapy in HER2/neu-negative breast cancer. Ann Oncol. 2006;17:588–596
- Comparison of rapidly cycled tandem high-dose chemotherapy plus peripheral-blood stem-cell support versus dose-dense conventional chemotherapy for adjuvant treatment of high-risk breast cancer: Results of a multicentre phase III trial. Lancet. 2005;366:1935–1944
- Adjuvant docetaxel for node-positive breast cancer. N Engl J Med. 2005;352:2302–2313
- High-dose chemotherapy for triple negative breast cancer. Ann Oncol. 2007;18:202–203
- Protein expression profiling in high-risk breast cancer patients treated with high-dose or conventional dose-dense chemotherapy. Clin Cancer Res. 2007;13:488–497
- A randomized trial of high-dose chemotherapy (HDC) with autologous peripheral blood stem cell support (ASCT) compared to standard therapy in women with metastatic breast cancer: A National Cancer Institute of Canada (NCIC) clinical trials group study. (abstract) Proc Am Soc Clin Oncol. 2001;20:21a;(abstr)
- Conventional-dose chemotherapy compared with high-dose chemotherapy plus autologous hematopoietic stem cell transplantation for metastatic breast cancer (Philadelphia Bone Marrow Transplant Group). N Engl J Med. 2000;342:1069–1076
- Conventional-dose chemotherapy compared with high-dose chemotherapy (HDC) plus autologous stem cell transplantation (SCT) for metastatic breast cancer: 5-year update of the ‘Philadelphia Trial’ (PBT-1). Proc Am Soc Clin Oncol. 2002;69:43a;(abstr)
- High dose thiotepa, cyclophosphamide and stem cell transplantation after 4 FEC 100 compared with 4 FEC alone allowed a better disease free survival but the same overall survival in first line chemotherapy for metastatic breast cancer (Results of the PEGASE 03 French Protocol). Proc Am Soc Clin Oncol. 2002;21:42a;(abstr)
- High-dose chemotherapy with haematopoietic stem cell transplantation for metastatic breast cancer patients: Final results of the French multicentric randomised CMA/PEGASE 04 protocol. Eur J Cancer. 2005;41:71–80
- A randomized phase III comparative trial of immediate consolidation with high-dose chemotherapy and autologous peripheral blood progenitor cell support compared to observation with delayed consolidation in women with metastatic breast cancer and only bone metastases following intensive induction chemotherapy. Bone Marrow Transplant. 2006;37:1009–1015
- Consolidation with high-dose combination alkylating agents with bone marrow transplantation significantly improves disease-free survival in hormone-insensitive metastatic breast cancer in complete remission compared with intensive standard-dose chemotherapy alone. Biol Blood Marrow Transplant. 2006;12:195–203
- Up-front tandem high-dose chemotherapy compared with standard chemotherapy with doxorubicin and paclitaxel in metastatic breast cancer: results of a randomized trial. J Clin Oncol. 2005;23:432–440
- Superiority of tandem high-dose chemotherapy (HDC) versus optimized conventionally-dosed chemotherapy (CDC) in patients (patients) with metastatic breast cancer (MBC): The International Randomized Breast Cancer Dose Intensity Study (IBDIS). Proc Am Soc Clin Oncol. 2003;22:23;(abstr)
- Prognostic model for relapse after high-dose chemotherapy with autologous stem-cell transplantation for stage IV oligometastatic breast cancer. J Clin Oncol. 2002;20:707–718
- Complete response after high-dose chemotherapy and autologous hemopoietic stem cell transplantation in metastatic breast cancer results in survival benefit. Breast J. 2006;12:531–235
- Randomized trial of single compared with tandem high-dose chemotherapy followed by autologous stem-cell transplantation in patients with chemotherapy-sensitive metastatic breast cancer. J Clin Oncol. 2006;24:3919–3926
- High dose chemotherapy with autologous hematopoietic stem cell support for solid tumors other than breast cancer in adults. Ann Oncol. 2006;17:1479–1488
- . Hematopoietic stem cell transplantation for small cell lung cancer. Chest. 1999;116(suppl 6):531S–538S
- Late intensification chemotherapy with autologous bone marrow transplantation in selected small-cell carcinoma of the lung; a randomized study. J Clin Oncol. 1987;5:1864–1873
- Use of hematopoietic progenitors in whole blood to support dose-dense chemotherapy: A randomized phase II trial in small-cell lung cancer patients. J Clin Oncol. 2001;19:712–719
- . Randomized phase III trial of dose-dense chemotherapy supported by whole blood hematopoietic progenitors in better-prognosis small-cell lung cancer. J Natl Cancer Inst. 2005;97:666–674
- High-dose sequential chemotherapy supported by peripheral blood progenitor cells for the treatment of small cell lung cancer (SCLC): Results of the EBMT Random-ICE trial. Proc EBMT Bone Marrow Transplant. 2007;39:O172;(abstr)
- . Chemotherapy advances in small cell lung cancer. Ann Oncol. 2006;17(suppl 5):v99–v102
- Paclitaxel plus ifosfamide followed by high-dose carboplatin plus etoposide in previously treated germ cell tumors. J Clin Oncol. 2007;25:85–90
- . High-dose chemotherapy and stem cell rescue for metastatic germ-cell tumors. N Engl J Med. 2007;357:340–348
- Refractory germ cell tumors (GCTs): Salvage high-dose chemotherapy(HD-CT) combining 2 mobilization regimes followed by 3 GD-CT with peripheral blood stem cell transplantation PBSCT: The TAXIF regimen (GETUG). Ann Oncol. 2005;16:411–418
- High-dose chemotherapy as salvage treatment in germ cell tumors: A multivariate analysis of prognostic variables. J Clin Oncol. 1996;14:2638–2645
- Salvage high-dose chemotherapy in patients with germ cell tumors: An Italian experience with 84 patients. Cancer. 2002;95:309–315
- High dose chemotherapy as initial salvage chemotherapy in patients with relapsed testicular cancer. J Clin Oncol. 2000;18:3346–3351
- A randomised trial of high-dose chemotherapy in the salvage treatment of patients failing first-line platinum chemotherapy for advanced germ cell tumors. Ann Oncol. 2005;16:1152–1159
- Long-term results of the first-line sequential high-dose etoposide, ifosfamide, and cisplatin chemotherapy plus autologous stem cell support for patients with advanced metastatic germ cell cancer: an extended phase I/II study of the German Testicular Cancer Study Group. J Clin Oncol. 2003;21:4083–4091
- First-line high-dose chemotherapy for patients with poor prognosis extragonadal germ cell tumors: The experience of the European Group for Blood and Marrow Transplantation (EBMT) Solid Tumors Working Party. Bone Marrow Transplant. 2004;34:1033–1037
- First-line sequential high-dose VIP chemotherapy with autologous transplantation for patients with primary mediastinal nonseminomatous germ cell tumours: A prospective trial. Br J Cancer. 2003;89:29–35
- Phase III randomised trial of conventional-dose chemotherapy and autologous hematopoietic stem-cell rescue as first-line treatment for patients with poor-prognosis metastatic germ cell tumors. J Clin Oncol. 2007;25:247–256
- . Survival of non-seminomatous germ cell cancer patients according to the IGCC classification: An update based on meta-analysis. Eur J Cancer. 2006;42:820–826
- High-dose chemotherapy with autologous transplantation for persistent/relapsed ovarian cancer: A multivariate analysis of survival for 100 consecutively treated patients. J Clin Oncol. 1997;15:1309–1317
- High-dose chemotherapy with hematopoietic rescue in patients with stage III to IV ovarian cancer: Long term results. J Clin Oncol. 1997;15:1302–1308
- High-dose chemotherapy for ovarian carcinoma: Long term results from the Solid Tumour Registry of the European Group for Blood and Marrow Transplantation (EBMT). Ann Oncol. 2001;12:639–699
- High-dose chemotherapy and autologous stem-cell transplantation for ovarian cancer: An autologous blood and marrow transplant registry. Ann Intern Med. 2000;133:504–515
- Phase III randomised trial of high-dose chemotherapy (HDC) and peripheral blood stem cells (PBSC) support as consolidation in patients (patients) with responsive low-burden advanced ovarian cancer (AOC): A 5-year follow-up of a GINECO/FNCLCC/SFGM–TC study. Proc Am Soc Clin Oncol. 2004;22:5006;(abstr)
- A phase III randomised trial of sequential high dose chemotherapy (HDC) for first-line treatment of ovarian cancer. Proc Am Soc Clin Oncol. 2005;23:5006;(abstr)
- . What is the role of high-dose chemotherapy in the era of targeted therapies?. J Clin Oncol. 2004;22:2263–2266
- Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med. 2005;353:1659–1672
- Lapatinib plus capecitabine for HER2-positive advanced breast cancer. N Engl J Med. 2006;355:2733–2743
- . Towards the integration of hematopoietic stem cells into therapy of breast cancer?. Haematologica. 1999;84:865–867
Supported in part by grant regionale 2005, Associazione Italiana per la Ricerca sul Cancro (AIRC) to P.P. and Oncologia Ca’ Granda ONLUS Fondazione to P.P. and S.S
PII: S0037-1963(07)00125-4
doi: 10.1053/j.seminhematol.2007.08.009
© 2007 Elsevier Inc. All rights reserved.
« Previous
Seminars in Hematology
Volume 44, Issue 4
, Pages 286-295
, October 2007
