« Previous
Next »
Seminars in Hematology
Volume 44, Issue 3
, Pages 138-147
, July 2007
Hematopoietic Growth Factors in the Treatment of Acquired Bone Marrow Failure States
References
- . Hematopoietic growth factors in the pathogenesis and for the treatment of aplastic anemia. Semin Hematol. 2000;37:81–90
- Long-term improvement of anaemia in a patient with aplastic anaemia by short term administration of pegylated recombinant human megakaryocyte growth and development factor. Br J Haematol. 2004;125:818–819
- Haemopoietic growth factors in aplastic anaemia: A cautionary note. Lancet. 1994;344:172–173
- . Increased apoptosis in aplastic anaemia bone marrow progenitor cells: Possible pathophysiological significance. Exp Haematol. 1995;23:1642–1648
- Collection of peripheral blood haemopoietic progenitors (PBHP) from patients with severe aplastic anaemia (SAA) after prolonged administration of granulocyte colony stimulating factor. Blood. 1993;82:1410–1414
- . Aplastic anaemia: Evidence for dysfunctional bone marrow progenitor cells and the corrective effect of granulocyte colony stimulating factor in vitro. Blood. 1996;87:3179–3185
- Antilymphocyte globulin, cyclosporine, prednisolone, and granulocyte colony-stimulating factor for severe aplastic anemia: An update of the GITMO/EBMT study on 100 patients. Blood. 2000;95:1931–1934
- Rabbit antithymocyte globulin (r-ATG) plus cyclosporine and granulocyte colony stimulating factor is an effective treatment for aplastic anaemia patients unresponsive to a first course of intensive immunosuppressive therapy. Br J Haematol. 1999;107:330–334
- Treatment of acquired severe aplastic anaemia: Bone marrow transplantation compared with immunosuppressive therapy—The European Group for Blood and Marrow Transplantation experience. Semin Hematol. 2000;37:69–80
- Results and follow-up of a phase III randomized study of recombinant human-granulocyte stimulating factor as support for immunosuppressive therapy in patients with severe aplastic anaemia. Br J Haematol. 2002;119:1075–1082
- Tichelli A: Presented at Bone Marrow Failure Scientific Symposium, Washington DC, October 17-19, 2005
- Myelodysplastic syndrome and acute myelogenous leukemia as a late clonal complication in children with acquired aplastic anemia. Blood. 1997;90:1009–1013
- Immunosuppressive therapy using antithymocyte globulin, cyclosporine, and danazol with or without human granulocyte colony-stimulating factor in children with acquired aplastic anemia. Blood. 2000;96:2049–2054
- Risk factors for evolution of acquired aplastic anemia into myelodysplastic syndrome and acute myeloid leukemia after immunosuppressive therapy in children. Blood. 2002;100:786–790
- Ten year outcome of acquired aplastic anaemia children treated with antithymocyte globulin, cyclosporine with or without G-CSF. Blood. 2006;108:126;(abstr)
- Treatment of severe aplastic anaemia with antilymphocyte globulin, cyclosporine and two different granulocyte colony-stimulating factor regimens: A GITMO prospective randomised study. Haematologica. 2004;89:1054–1061
- Immunosuppressive therapy for aplastic anaemia in children: A more severe disease predicts better survival. Blood. 2005;106:2102–2104
- . Treatment of aplastic anaemia with granulocyte-colony stimulating factor and risk of malignancy. Lancet. 2001;357:43–44
- Granulocyte-stimulating factor and severe aplastic anaemia: A survey by the European Group for Blood and Marrow Transplantation (EBMT). Blood. 2007;109:2794–2796
- Malignant tumors occurring after treatment of aplastic anemia. N Engl J Med. 1993;329:1152–1157
- . Immunosuppressive therapy for acquired severe aplastic anemia (SAA): A prospective comparison of four different regimens. Exp Hematol. 2006;34:826–831
- . Hematopoietic growth factors in the treatment of the myelodysplastic syndromes. Curr Opin Hematol. 1995;2:204–209
- International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood. 1997;89:2079–2088
- on the role of epoietin alpha in hematologic malignancies and myelodysplastic syndromes. Semin Oncol. 1998;25(suppl 7):12–18
- . Cytokine targets in the treatment of myelodysplastic syndromes. Curr Hematol Rep. 2005;4:429–435
- Effect of recombinant human erythropoietin combined with granulocyte/macrophage colony-stimulating factor in the treatment of patients with myelodysplastic syndrome. Blood. 2000;95:1175–1179
- Granulocyte colony-stimulating factor inhibits spontaneous cytochrome c release and mitochondria-dependent apoptosis of myelodysplastic syndrome hematopoietic progenitors. Blood. 2003;101:1080–1086
- . Expression and functional analysis of granulocyte colony-stimulating factor receptors on CD34++ cells in patients with myelodysplastic syndrome (MDS) and MDS-acute myeloid leukaemia. Br J Haematol. 2003;121:63–75
- Novel variant isoform of G-CSF receptor involved in induction of proliferation of FDCP-2 cells: Relevance to the pathogenesis of myelodysplastic syndrome. J Cell Physiol. 2002;191:327–335
- Granulocyte colony-stimulating factor administration upregulates telomerase activity in CD34+ haematopoietic cells and may prevent telomere attrition after chemotherapy. Br J Haematol. 2003;120:329–336
- . Erythropoietin receptor in myelodysplastic syndrome and leucemia. Leuk Lymphoma. 2002;43:261–264
- Erythropoietin-dependent transformation of myelodysplastic syndrome to acute monoblastic leukemia. Blood. 2001;98:3492–3494
- Granulocyte colony-stimulating factor preferentially stimulates proliferation of monosomy 7 cells bearing the isoform IV receptor. Proc Natl Acad Sci U S A. 2006;103:14483–14488
- Antiapoptotic role of growth factors in the myelodysplastic syndromes: Concordance between in vitro and in vivo observations. Clin Cancer Res. 2005;11:6291–6299
- . Long-term outcome of treatment of anemia in MDS with erythropoietin and G-CSF. Blood. 2005;106:803–811
- In patients with myelodysplastic syndromes response to rHuEPO and G-CSF treatment is related to an increase of cytogenetically normal CD34 cells. Br J Haematol. 2004;126:501–507
- . Haemato-Oncology Task Force of the British Committee for Standards in Haematology: Guidelines on the use of colony-stimulating factors in haematological malignancies. Br J Haematol. 2003;123:22–33
- 2006 update of recommendations for the use of white blood cell growth factors: An evidence-based clinical practice guideline. J Clin Oncol. 2006;24:3187–3205
- . Colony-stimulating factors in the management of neutropenia and its complications. Ann Hematol. 2005;84:697–708
- Phase III randomized multicenter trial of G-CSF vs. observation for myelodysplastic syndromes (MDS). Blood. 1993;82:196a;(suppl 1, abstr)
- . Growth factor priming in therapy of acute myelogenous leukemia. Curr Hematol Rep. 2004;3:413–418
- Low-dose cytosine arabinoside (LD-AraC) vs LD-AraC plus granulocyte/macrophage colony stimulating factor vs LD-AraC plus interleukin-3 for myelodysplastic syndrome patients with a high risk of developing acute leukemia: Final results of a randomized phase III study (06903) of the EORTC Leukemia Cooperative Group. Leukemia. 2005;19:1929–1933
- Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia. Blood. 2006;108:419–425
- . A randomised double-blind placebo-controlled study with subcutaneous recombinant human erythropoietin in patients with low-risk myelodysplastic syndromes. Br J Haematol. 1998;103:1070–1074
- Prolonged administration of erythropoietin increases erythroid response rate in myelodysplastic syndromes: A phase II trial in 281 patients. Br J Haematol. 2002;118:174–180
- Efficacy of a single, weekly dose of recombinant erythropoietin in myelodysplastic syndromes. Br J Haematol. 2003;122:269–271
- . Once-weekly dosing of recombinant human erythropoietin alpha in patients with myelodysplastic syndromes unresponsive to conventional dosing. Ann Oncol. 2004;15:1684–1690
- Impact of a new dosing regimen of epoetin alfa on quality of life and anemia in patients with low-risk myelodysplastic syndrome. Ann Hematol. 2005;84:167–176
- Quality of life and brain function following high-dose recombinant human erythropoietin in low-risk myelodysplastic syndromes: A preliminary report. Eur J Haematol. 2004;72:113–120
- Darbepoetin alpha for the treatment of anemia in patients with myelodysplastic syndromes. Cancer. 2006;107:2807–2816
- Darbepoetin alpha for the treatment of anaemia in low-intermediate risk myelodysplastic syndromes. Br J Haematol. 2005;128:204–209
- . Darbepoetin alfa for the treatment of anemic patients with low- and intermediate-1-risk myelodysplastic syndromes. Ann Oncol. 2005;16:1921–1927
- High-dose darbepoetin alpha in the treatment of anaemia of lower risk myelodysplastic syndrome results of a phase II study. Br J Haematol. 2006;133:513–519
- Erythropoietin plus granulocyte colony-stimulating factor in the treatment of myelodysplastic syndromes (Identification of a subgroup of responders). Haematologica. 1999;84:1058–1064
- Adding growth factors or interleukin-3 to erythropoietin has limited effects on anemia of transfusion-dependent patients with myelodysplastic syndromes unresponsive to erythropoietin alone. Haematologica. 2001;86:44–51
- . Recombinant human erythropoietin in combined treatment with granulocyte- or granulocyte-macrophage colony-stimulating factor in patients with myelodysplastic syndromes. J Cancer Res Clin Oncol. 2002;128:497–502
- Health, economic, and quality-of-life effects of erythropoietin and granulocyte colony-stimulating factor for the treatment of myelodysplastic syndromes: A randomized, controlled trial. Blood. 2004;104:321–327
- Erythropoietin plus granulocyte colony-stimulating factor is better than erythropoietin alone to treat anemia in low-risk myelodysplastic syndromes: Results from a randomized single-centre study. Ann Hematol. 2006;85:174–180
- Improved multilineage response of hematopoiesis in patients with myelodysplastic syndromes to a combination therapy with all-trans-retinoic acid, granulocyte colony-stimulating factor, erythropoietin and alpha-tocopherol. Ann Hematol. 1996;72:237–244
- . Combination of erythropoietin and thalidomide for the treatment of anemia in patients with myelodysplastic syndromes. Leuk Res. 2006;30:385–388
- . Thromboembolic events in patients with myelodysplastic syndrome receiving thalidomide in combination with darbepoietin-alpha. Br J Haematol. 2003;121:101–103
- . Response to erythropoietin and moxifloxacin in a patient with myelodysplastic syndrome non-respondent to erythropoietin alone. Eur J Intern Med. 2002;13:521–523
- Successful treatment of refractory anemia with a combination regimen containing recombinant human erythropoietin, low-dose methylprednisolone and nandrolone. J Exp Clin Cancer Res. 2004;23:47–52
- Thrombopoietin stimulates myelodysplastic syndrome granulocyte-macrophage and erythroid progenitor proliferation. Leuk Lymphoma. 1998;30:279–292
- . Long-term administration of pegylated recombinant human megakaryocyte growth and development factor dramatically improved cytopenias in a patient with myelodysplastic syndrome. Br J Haematol. 2003;122:764–767
- . Phase II study of low-dose interleukin-11 in patients with myelodysplastic syndrome. Leuk Lymphoma. 2006;47:2049–2054
- Adaptive randomized study of idarubicin and cytarabine alone or with interleukin-11 as induction therapy in patients aged 50 or above with acute myeloid leukemia or high-risk myelodysplastic syndromes. Leuk Res. 2005;29:649–652
- Erythroid response to treatment with G-CSF plus erythropoietin for the anaemia of patients with myelodysplastic syndromes: proposal for a predictive model. Br J Haematol. 1997;99:344–351
- A validated decision model for treating the anaemia of myelodysplastic syndromes with erythropoietin + granulocyte colony-stimulating factor: significant effects on quality of life. Br J Haematol. 2003;120:1037–1046
- . Baseline and early treatment factors are not clinically useful for predicting individual response to erythropoietin in anemic cancer patients. Oncologist. 2003;8:99–107
- Predicting erythroid response to recombinant erythropoietin plus granulocyte colony-stimulating factor therapy following a single subcutaneous bolus in patients with myelodysplasia. Haematologica. 2006;91:709–710
- . A decision analysis to determine the appropriate treatment for low-risk myelodysplastic syndromes. Cancer. 2007;109:1125–1132
PII: S0037-1963(07)00064-9
doi: 10.1053/j.seminhematol.2007.04.010
© 2007 Elsevier Inc. All rights reserved.
« Previous
Next »
Seminars in Hematology
Volume 44, Issue 3
, Pages 138-147
, July 2007
