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Seminars in Hematology
Volume 44, Issue 2
, Pages 106-113
, April 2007
Inherited Thrombophilia in Arterial Disease: A Selective Review
References
- . Role of hemostatic gene polymorphisms in venous and arterial thrombotic disease. Blood. 2000;95:1517–1532
- . Thrombophilia, polymorphisms, and vascular disease. Mol Pathol. 2000;53:300–306
- . Hemostatic risk factors and arterial thrombotic disease. Thromb Haemost. 2001;85:584–595
- . Genetic polymorphisms associated with venous and arterial thrombosis: An overview. Arch Pathol Lab Med. 2002;126:295–304
- Laboratory evaluation of hypercoagulability with venous or arterial thrombosis. Arch Pathol Lab Med. 2002;126:1281–1295
- . Assessment of hemostatic risk factors in predicting arterial thrombotic events. Arterioscler Thromb Vasc Biol. 2005;25:2043–2053
- . Editorial comment—Routine thrombophilia testing in stroke patients is unjustified. Stroke. 2003;34:1826–1827
- . Is hypercoagulability an issue in arterial thrombosis? (No). J Thromb Haemost. 2004;2:692–694
- . Is hypercoagulability an issue in arterial thrombosis? (Yes). J Thromb Haemost. 2004;2:690–691
- . Factor V Leiden: The Copenhagen City Heart Study and 2 meta-analyses. Blood. 2002;100:3–10
- . Association between factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations and events of the arterial circulatory system: A meta-analysis of published studies. Am Heart J. 2003;146:948–957
- Seven haemostatic gene polymorphisms in coronary disease: Meta-analysis of 66,155 cases and 91,307 controls. Lancet. 2006;367:651–658
- . Combined carrier status of prothrombin 20210A and factor XIII-A Leu34 alleles as a strong risk factor for myocardial infarction: Evidence of a gene-gene interaction. Blood. 2003;101:3037–3041
- . Prevalence of resistance against activated protein C resulting from factor V Leiden is significantly increased in myocardial infarction: investigation of 507 patients with myocardial infarction. Am Heart J. 2004;147:897–904
- G20210A prothrombin gene variant and clinical outcome in patients with a first acute coronary syndrome. Haematologica. 2004;89:1134–1138
- Myocardial infarction under the age of 36: Prevalence of thrombophilic disorders. Thromb Haemost. 2003;90:272–278
- High prevalence of thrombophilia among young patients with myocardial infarction and few conventional risk factors. Int J Cardiol. 2005;98:421–424
- . Difference in absolute risk of venous and arterial thrombosis between familial protein S deficiency type I and type III (Results from a family cohort study to assess the clinical impact of a laboratory test-based classification). Br J Haematol. 2005;128:703–710
- . Meta-analysis of genetic studies in ischemic stroke: Thirty-two genes involving approximately 18,000 cases and 58,000 controls. Arch Neurol. 2004;61:1652–1661
- Factor V Leiden and prothrombin G20210A mutations in young adults with cryptogenic ischemic stroke. Thromb Haemost. 2004;91:1031–1034
- Polymorphisms in prothrombotic genes and their impact on ischemic stroke in a Sardinian population. Thromb Haemost. 2005;93:1095–1100
- . Different incidence of venous thrombosis in patients with inherited deficiencies of antithrombin III, protein C and protein S. Thromb Haemost. 1994;71:15–18
- Prospective study of markers of hemostatic function with risk of ischemic stroke. Circulation. 1999;100:736–742
- . Association of hemostatic variables with MRI-detected cerebral abnormalities: The Atherosclerosis Risk in Communities Study. Neuroepidemiology. 2001;20:96–104
- . Inherited thrombophilia in ischemic stroke and its pathogenic subtypes. Stroke. 2001;32:1793–1799
- . Studies on congenital protein C deficiency in Japanese: prevalence, genetic analysis, and relevance to the onset of arterial occlusive diseases. Semin Thromb Hemost. 2000;26:11–16
- Different risks of thrombosis in four coagulation defects associated with inherited thrombophilia: A study of 150 families. Blood. 1998;92:2353–2358
- . Thrombophilia and first arterial ischaemic stroke: A systematic review. Arch Dis Child. 2005;90:402–405
- Prospective assessment of risk factors for recurrent stroke during childhood—A 5-year follow-up study. Lancet. 2002;360:1540–1545
- Symptomatic ischemic stroke in full-term neonates: Role of acquired and genetic prothrombotic risk factors. Stroke. 2000;31:2437–2441
- Prothrombotic disorders and abnormal neurodevelopmental outcome in infants with neonatal cerebral infarction. Pediatrics. 2001;107:1400–1404
- . Factor V Leiden and prothrombin gene mutation may predispose to paradoxical embolism in subjects with patent foramen ovale. Blood Coagul Fibrinolysis. 2003;14:261–268
- Inherited thrombophilic disorders in young adults with ischemic stroke and patent foramen ovale. Stroke. 2003;34:28–33
- Young Adult Myocardial Infarction and Ischemic Stroke: The role of paradoxical embolism and thrombophilia (The YAMIS Study). J Am Coll Cardiol. 2006;48:686–691
- Factor II G20210A and factor V G1691A gene mutations and peripheral arterial occlusive disease. Thromb Haemost. 2000;83:20–22
- Activated protein C resistance, factor V Leiden and peripheral vascular disease. Cardiovasc Surg. 1997;5:157–160
- . Activated protein C resistance in patients with peripheral vascular disease. J Vasc Surg. 1998;28:624–629
- The factor II G20210A gene polymorphism, but not factor V Arg506Gln, is associated with peripheral arterial disease: Results of a case-control study. J Thromb Haemost. 2004;2:1334–1340
- Factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations are not associated with chronic limb ischemia: The Linz Peripheral Arterial Disease (LIPAD) study. J Vasc Surg. 2005;41:808–815
- Thrombophilic risk factors for symptomatic peripheral arterial disease. J Vasc Surg. 2005;41:255–260
- Hypercoagulable states in patients with leg ischaemia. Br J Surg. 1994;81:811–814
- . Hypercoagulable abnormalities and postoperative failure of arterial reconstruction. Eur J Endovasc Surg. 1997;17:363–370
- Hypercoagulable states and lower limb ischemia in young adults. J Vasc Surg. 1989;9:334–341
- Hereditary protein S deficiency in young adults with arterial occlusive disease. Thromb Haemost. 1990;64:206–210
- . Arterial thromboembolic events in patients with the factor V Leiden mutation. Am J Surg. 1998;176:122–125
- . Mortality and causes of death in families with the factor V Leiden mutation (resistance to activated protein C). Blood. 1997;89:1963–1967
- Homozygosity for factor V Leiden leads to enhanced thrombosis and atherosclerosis in mice. Circulation. 2005;111:1822–1825
- . Myocardial infarction in young adults: Angiographic characterization, risk factors and prognosis (Coronary Artery Surgery Study Registry). J Am Coll Cardiol. 1995;26:54–661
- Factor V Leiden increases the risk of myocardial infarction in young women. Blood. 1997;89:2817–2821
- . A common prothrombin variant (20210 G to A) increases the risk of myocardial infarction in young women. Blood. 1997;90:1747–1750
- . Prothrombotic conditions, oral contraceptives, and the risk of ischemic stroke. J Thromb Haemost. 2005;3:1213–1217
- . Oral contraceptive use, thrombophilia and their interaction in young women with ischemic stroke. Haematologica. 2006;91:844–847
- . Prevalence and risk of thrombophilia defects in vascular patients. Eur J Vasc Endovasc Surg. 2004;28:124–131
- . Comparison of the prevalence of APC-resistance in vascular patients and in a normal population cohort in Western Germany. Eur J Vasc Endovasc Surg. 2005;30:160–163
- . The prevalence of thrombophilia in patients with symptomatic peripheral vascular disease. Br J Surg. 2006;93:577–581
- An association between atherosclerosis and venous thrombosis. N Engl J Med. 2003;348:1435–1441
- A prospective study on cardiovascular events after acute pulmonary embolism. Eur Heart J. 2005;26:77–83
- Incidence of arterial cardiovascular events in patients with idiopathic venous thromboembolism (A retrospective cohort study). Thromb Haemost. 2006;96:132–136
- Venous thromboembolism and the risk of subsequent symptomatic atherosclerosis. J Thromb Haemost. 2006;4:1891–1896
- . Incidence and risk of venous thromboembolism in patients with verified arterial thrombosis: A population study based on 23,796 consecutive autopsies. J Thromb Haemost. 2006;4:1897–1902
- Subclinical atherosclerosis and the risk of future venous thrombosis in the Cardiovascular Health Study. J Thromb Haemost. 2006;4:1903–1908
- Prospective study of subclinical atherosclerosis as a risk factor for venous thromboembolism. J Thromb Haemost. 2006;4:1909–1913
- A prospective study of risk factors for pulmonary embolism in women. JAMA. 1997;277:642–645
- . Obesity as a risk factor in venous thromboembolism. Am J Med. 2005;118:978–980
- . The risk of venous thromboembolism is markedly elevated in patients with diabetes. Diabetologia. 2005;8:1017–1021
- . High-density lipoprotein deficiency and dyslipoproteinemia associated with venous thrombosis in men. Circulation. 2005;112:893–899
- . Risk of arterial thrombosis in carriers of familial thrombophilia. J Thromb Haemost. 2006;4:916–918
- Arterial wall thickness and the risk of recurrent ischemic events in carriers of the prothrombin G20210A mutation with clinical manifestations of atherosclerosis. Atherosclerosis. 2002;163:135–140
- The heterozygous 20210 G/A prothrombin genotype is associated with early venous thrombosis in inherited thrombophilias and is not increased in frequency in artery disease. Arterioscler Thromb Vasc Biol. 1997;17:1325–1330
- . No evidence of association between prothrombotic gene polymorphisms and the development of acute myocardial infarction at a young age. Circulation. 2003;107:1117–1122
- A prospective cohort study on the absolute incidence of venous thromboembolism and arterial cardiovascular disease in asymptomatic carriers of the prothrombin 20210A mutation. Blood. 2006;108:2604–2607
- . Association of ABO histo-blood group B allele with myocardial infarction. Eur J Immunogenetics. 2003;30:201–206
- . Antithrombotic therapy for venous thromboembolic disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004;126(suppl):401S–428S
PII: S0037-1963(07)00009-1
doi: 10.1053/j.seminhematol.2007.01.008
© 2007 Elsevier Inc. All rights reserved.
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Seminars in Hematology
Volume 44, Issue 2
, Pages 106-113
, April 2007
