Seminars in Hematology
Volume 43 , Pages S39-S42 , October 2006

Intravenous Iron in Cardiac Surgery

  • Manuel Muñoz

      Affiliations

    • GIEMSA, School of Medicine, University of Málaga, Málaga, Spain.
    • Corresponding Author InformationAddress correspondence to Manuel Muñoz, MD, PhD, GIEMSA, Facultad de Medicina, Universidad de Málaga, Campus de Teatinos, s/n, 29071 Málaga, Spain.
    • ,
  • Ramón Leal-Noval

      Affiliations

    • Department of Intensive Care, University Hospital “Virgen del Rocio,” Seville, Spain.
    • ,
  • José Antonio García-Erce

      Affiliations

    • Department of Hematology, University Hospital “Miguel Servet,” Zaragoza, Spain.

References 

  1. Leal-Noval SR, Jara-López I, García-Garmendia JL, Marín-Niebla A, Herruzo-Avilés A, Camacho-Laraña P, et al. Influence of erythrocyte concentrate storage time on postsurgical morbidity in cardiac surgery patients. Anesthesiology. 2003;98:815–822
  2. Khanna MP, Hebert PC, Fergusson DA. Review of the clinical practice literature on patient characteristics associated with perioperative allogeneic red blood cell transfusion. Transfus Med Rev. 2003;17:110–119
  3. Koch CG, Weng Y, Zhou SX, Savino JS, Mathew JP, Hsu PH, et al. Prevalence of risk factors, and not gender per se, determines short- and long-term survival alter coronary artery bypass surgery. J Cardiothorac Vasc Anesth. 2003;17:585–593
  4. Muñoz M, Garcia-Erce JA, Leal-Noval SR. Perioperative transfusion in anaemic patients undergoing coronary artery bypass. Lancet. 2002;360:1427–1428
  5. Muñoz M, Campos A, García-Erce JA, Ramírez G. Fisiopatología del metabolismo del hierro: Implicaciones diagnósticas y terapéuticas. Nefrología. 2005;25:9–19
  6. Fernández MA, Cobos A, Ariza A, Muñoz E, Ramírez G, Muñoz M. Postoperative erythropoiesis is blunted in patients undergoing cardiac surgery. Transfusion Alternatives Transfusion Med. 2006;8:61;(suppl, abstr)
  7. Fernández MA, García-Pinilla JM, Jiménez M, Muñoz E, Campos A, Muñoz M. Preoperative anemia in cardiac surgery (Role of angiotensin-converting enzyme inhibitors). TATM. 2006;8:60;(suppl, abstr)
  8. Kyo S, Omoto R, Hirashima K, Eguchi S, Fujita T. Effect of human recombinant erythropoietin on reduction of homologous blood transfusion in open-heart surgery (A Japanese multicenter study). Circulation. 1992;86(suppl):II413–II418
  9. Sowade O, Messinger D, Franke W, Sowade B, Scigalla P, Warnke H. The estimation of efficacy of oral iron supplementation during treatment with epoetin beta (recombinant human erythropoietin) in patients undergoing cardiac surgery. Eur J Haematol. 1998;60:252–259
  10. D’Ambra MN, Gray RJ, Hillman R, Jones JW, Kim HC, Rawitscher R, et al. Effect of recombinant human erythropoietin on transfusion risk in coronary bypass patients. Ann Thorac Surg. 1997;64:1686–1693
  11. Shimpo H, Mizumoto T, Onoda K, Yuasa H, Yada I. Erythropoietin in pediatric cardiac surgery: Clinical efficacy and effective dose. Chest. 1997;111:1565–1570
  12. Kiyama H, Ohshima N, Imazeki T, Yamada T. Autologous blood donation with recombinant human erythropoietin in anemic patients. Ann Thorac Surg. 1999;68:1652–1656
  13. Sonzogni V, Crupi G, Poma R, Annechino F, Ferri F, Filisetti P, et al. Erythropoietin therapy and preoperative autologous blood donation in children undergoing open heart surgery. Br J Anaesth. 2001;87:429–434
  14. Watanabe Y, Fuse K, Naruse Y, Kobayashi T, Yamamoto S, Konishi H, et al. Subcutaneous use of erythropoietin in heart surgery. Ann Thorac Surg. 1992;54:479–483
  15. Schmoeckel M, Nollert G, Mempel M, Mempel W, Reichart B. Effects of recombinant human erythropoietin on autologous blood donation before open heart surgery. Thorac Cardiovasc Surg. 1993;41:364–368
  16. Kulier AH, Gombotz H, Fuchs G, Vuckovic U, Metzler H. Subcutaneous recombinant human erythropoietin and autologous blood donation before coronary artery bypass surgery. Anesth Analg. 1993;76:102–106
  17. Hayashi J, Kumon K, Takanashi S, Kawashima Y, Eguchi S, Takaku F, et al. Subcutaneous administration of recombinant human erythropoietin before cardiac surgery: A double-blind, multicenter trial in Japan. Transfusion. 1994;34:142–146
  18. Walpoth B, Galliker B, Spirig P, Haeberli A, Rosenmund A, Althaus U, et al. Use of epoetin alfa in autologous blood donation programs for patients scheduled for elective cardiac surgery. Semin Hematol. 1996;33(suppl 2):75–76
  19. Kobayashi T, Makuuchi H, Takahashi K, Furuse A, Shibata Y, Tsuno H, et al. Effects of recombinant human erythropoietin therapy on blood coagulation and fibrinolysis system. Ann Thorac Cardiovasc Surg. 2001;7:273–277
  20. Crosby L, Palarski VA, Cottington E, Cmolik B. Iron supplementation for acute blood loss anemia after coronary artery bypass surgery: A randomized, placebo-controlled study. Heart Lung. 1994;23:493–499
  21. Madi-Jebara S, Sleilaty GS, Achouh PE, Yazigi AG, Haddad FA, Hayek GM, et al. Postoperative intravenous iron used alone or in combination with low-dose erythropoietin in not effective for correction of anemia after cardiac surgery. J Cardiothorac Vasc Anesth. 2004;18:59–63
  22. Hulin S, Durandy Y. Intérět du fer intraveineux dans les anémies induites par l’hémodilution en chirurgie cardiaque pédiatrique. Ann Fran Anesth Reanim. 2005;24:1262–1265
  23. Karkouti K, McCluskey SA, Ghannam M, Salpeter MJ, Quirt I, Yau TM. Intravenous iron and recombinant erythropoietin for the treatment of postoperative anemia. Can J Anesth. 2006;53:11–19

PII: S0037-1963(06)00164-8

doi: 10.1053/j.seminhematol.2006.08.009

Seminars in Hematology
Volume 43 , Pages S39-S42 , October 2006

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