Seminars in Hematology
Volume 43 , Pages S36-S38 , October 2006

Intravenous Iron in Colorectal Cancer Surgery

  • Manuel Mun∼oz

      Affiliations

    • GIEMSA, School of Medicine, University of Málaga, Málaga, Spain.
    • Corresponding Author InformationAddress correspondence to Manuel Muñoz, MD, PhD, GIEMSA, Facultad de Medicina, Universidad de Málaga, Campus de Teatinos, s/n, 29071 Málaga, Spain.
    • ,
  • Arturo Campos

      Affiliations

    • Department of Hematology, University Hospital “Virgen de la Victoria,” Málaga, Spain.
    • ,
  • José Antonio García-Erce

      Affiliations

    • Department of Hematology, University Hospital “Miguel Servet,” Zaragoza, Spain.

References 

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  2. Beale AL, Penney MD, Allison MC. The prevalence of iron deficiency among patients presenting with colorectal cancer. Colorectal Dis. 2005;7:398–402
  3. Prutki M, Poljak-Blazi M, Jakopovic M, Tomas D, Stipancic I, Zarkovic N. Altered iron metabolism, transferrin receptor 1 and ferritin in patients with colon cancer. Cancer Lett. 2006;238:188–196
  4. Li F, Kishida T, Kobayashi M. Serum iron and ferritin levels in patients with colorectal cancer in relation to the size, site, and disease stage of cancer. J Gastroenterol. 1999;34:195–199
  5. Jensen LS, Puho E, Pedersen L, Mortensen FV, Sorensen HT. Long-term survival after colorectal surgery associated with buffy-coat-poor and leucocyte-depleted blood transfusion: A follow-up study. Lancet. 2005;365:681–682
  6. Vamvakas EC, Carven JH. Allogeneic blood transfusion, hospital charges, and length of hospitalization: A study of 487 consecutive patients undergoing colorectal cancer resection. Arch Pathol Lab Med. 1998;122:145–151
  7. Okuyama M, Ikeda K, Shibata T, Tsukahara Y, Kitada M, Shimano T. Preoperative iron supplementation and intraoperative transfusion during colorectal cancer surgery. Surg Today. 2005;35:36–40
  8. Campos A, Sevilla I, Baca JJ, Romero A, Ramírez G, Muñoz M. Perioperative iron therapy and transfusion requirements in patients undergoing surgery for colon cancer (Preliminary results). Transfusion Alternatives Transfusion Med. 2005;7(suppl):96;(abstr)
  9. Christodoulakis M, Tsiftsis DD Hellenic Surgical Oncology Perioperative EPO Study Group. Preoperative epoetin alfa in colorectal surgery: A randomized, controlled study. Ann Surg Oncol. 2005;12:718–725
  10. Kettelhack C, Hones C, Messinger D, Schlag PM. Randomized multicentre trial of the influence of recombinant human erythropoietin on intraoperative and postoperative transfusion need in anaemic patients undergoing right hemicolectomy for carcinoma. Br J Surg. 1998;85:63–67
  11. Qvist N, Boesby S, Wolff B, Hansen CP. Recombinant human erythropoietin and hemoglobin concentration at operation and during the postoperative period: Reduced need for blood transfusions in patients undergoing colorectal surgery—Prospective double-blind placebo-controlled study. World J Surg. 1999;23:30–35
  12. Braga M, Gianotti L, Gentilini O, Vignali A, Di Carlo V. Erythropietic response induced by recombinant human erythropoietin in anemic cancer patients candidate to major abdominal surgery. Hepatogastroenterology. 1997;44:685–690
  13. Kosmadakis N, Messaris E, Maris A, Katsaragakis S, Leandros E, Konstadoulakis MM, et al. Perioperative erythropoietin administration in patients with gastrointestinal tract cancer: prospective randomized double-blind study. Ann Surg. 2003;237:417–421
  14. Tsuji Y, Kambayashi J, Shiba E, Sakon M, Kawasaki T, Mori T. Effect of recombinant human erythropoietin on anaemia after gastrectomy: A pilot study. Eur J Surg. 1995;161:29–33
  15. Heiss MM, Tarabichi A, Delanoff C, Allgayer H, Jauch KW, Hernandez-Richter T, et al. Perisurgical erythropoietin application in anemic patients with colorectal cancer: A double-blind randomized study. Surgery. 1996;119:523–527
  16. Hoynck van Papendrecht MA, Hop W, Langenhorst BL, Kothe FC, Marquet RL, Jeekel J. Feasibility of a predeposit autologous blood donation program in colorectal cancer patients: Results from a randomized clinical study. Vox Sang. 1992;62:102–107
  17. Heiss MM, Mempel W, Jauch KW, Delanoff C, Mayer G, Mempel M, et al. Beneficial effect of autologous blood transfusion on infectious complications after colorectal cancer surgery. Lancet. 1993;342:1328–1333
  18. Busch OR, Hop WC, Hoynck van Papendrecht MA, Marquet RL, Jeekel J. Blood transfusions and prognosis in colorectal cancer. N Engl J Med. 1993;328:1372–1376
  19. Vignali A, Braga M, Dionigi P, Radaelli G, Gentilini O, Bellini A, et al. Impact of a programme of autologous blood donation on the incidence of infection in patients with colorectal cancer. Eur J Surg. 1995;161:487–492
  20. Braga M, Gianotti L, Vignali A, Gentilini O, Servida P, Bordignon C, et al. Evaluation of recombinant human erythropoietin to facilitate autologous blood donation before surgery in anaemic patients with cancer of the gastrointestinal tract. Br J Surg. 1995;82:1637–1640
  21. Rau B, Schlag PM, Willeke F, Herfarth C, Stephan P, Franke W. Increased autologous blood donation in rectal cancer by recombinant human erythropoietin (rhEPO). Eur J Cancer. 1998;34:992–998

PII: S0037-1963(06)00161-2

doi: 10.1053/j.seminhematol.2006.08.005

Seminars in Hematology
Volume 43 , Pages S36-S38 , October 2006

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