« Previous
Next »
Seminars in Hematology
Volume 43
, Pages S8-S13
, April 2006
Current Opinion on Inhibitor Treatment Options
References
-
.
Diagnosis and Management of Inhibitors to Factors VIII and IX. An Introductory Discussion for Physicians. Treatment of Hemophilia Monograph Series, No. 34
. Montreal, Québec, Canada: World Federation of Hemophilia; 2004;
- . Inhibitors (Resolving diagnostic and therapeutic dilemmas) . Haemophilia . 2002;8:280–287
- . The epidemiology of inhibitors in haemophilia A (A systemic review) . Haemophilia . 2003;9:418–435
-
.
New perspectives in hemophilia treatment
.
Hematology
. 2005;429–435
Am Soc Hematol Educ Program
- Proceedings (A more uniform measurement of factor VIII inhibitors) . Thromb Diath Haemorrh . 1975;34:612
- . Definitions in hemophilia. Recommendation of the scientific subcommittee on factor VIII and factor IX of the scientific and standardization committee of the International Society on Thrombosis and Haemostasis . Thromb Haemost . 2001;85:560
- . Transient inhibitors in the Recombinate PUP study . Thromb Haemost . 2000;84:145–146
-
.
Inhibitors in haemophilia
(Clinical aspects)
.
Haemophilia
. 2004;10(suppl 4):140–145
- . Prevention of bleeds in hemophilia patients with inhibitors (Emerging data and clinical direction) . Am J Hematol . 2004;77:187–193
- . Cost of care and quality of life for patients with hemophilia complicated by inhibitors (The COCIS Study Group) . Blood . 2003;102:2358–2363
- The incidence of factor VIII and factor IX inhibitors in the hemophilia population of the UK and their effect on subsequent mortality, 1977-99 . J Thromb Haemost . 2004;2:1047–1054
-
.
Literature review of surgery management in inhibitor patients
.
Haemophilia
. 2004;10(suppl 2):22–29
- Inhibitors in hemophilia A (Mechanisms of inhibition, management and perspectives) . Blood Coagul Fibrinolysis . 2004;15:109–124
- Autoplex versus proplex (A controlled, double-blind study of effectiveness in acute hemarthroses in hemophiliacs with inhibitors to factor VIII) . Blood . 1983;62:1135–1138
- . Multicenter retrospective study on the utilization of FEIBA in France in patients with factor VIII and factor IX inhibitors . Thromb Haemost . 1997;77:1113–1119 Factor Eight Bypassing Activity
-
.
FEIBA VH in home treatment—A 3-year prospective experience
.
In:
Haemophilia
. 4:
1998;p. 238;
Presented at the XXIII International Congress of the World Federation of Hemophilia in The Hague, The Netherlands. (abstr 33)
-
Immune tolerance induction (ITI) and factor VIII inhibitor bypass activity (FEIBA) for prophylaxis in patients with high responding inhibitors
.
Ann Hematol
. 2001;80(suppl 1):A38;
(abstr 138)
-
.
Efficacy and safety of factor VIII inhibitor bypass activity (Feiba) for long-term prophylaxis in patients with high-responding inhibitors
.
Blood
. 2000;96:265a;
(abstr 1140)
- . Prophylactic recombinant factor VIIa in haemophilia patients with inhibitors . Haemophilia . 2005;11:203–207
- . Effective prophylaxis with daily recombinant factor VIIa (rFVIIa-Novoseven) in a child with high titre inhibitors and a target joint . Thromb Haemost . 2001;86:1126–1127
-
.
High dose recombinant activated factor VII in a pediatric patient with factor VIII deficiency and high titer inhibitor
.
Blood
. 2003;102:104b;
(abstr 4128)
-
Epidemiology of inhibitors and current treatment strategies
.
Haematologica
. 2003;88:17–20
- . The diagnosis and management of factor VIII and IX inhibitors (A guideline from the UK Haemophilia Centre Doctors’ Organization (UKHCDO)) . Br J Haematol . 2000;111:78–90
-
.
Immunoadsorption for coagulation factor inhibitors
.
Transfusion
. 1991;31:265–269
-
.
Recombinant factor VIIa versus aPCCs in haemophiliacs with inhibitors
(Treatment and cost considerations)
.
Haemophilia
. 1999;5(suppl 3):43–49
- . The use of factor eight inhibitor by-passing activity (FEIBA immuno) product for treatment of bleeding episodes in hemophiliacs with inhibitors . Blood . 1983;61:36–40
-
.
Efficacy and safety of vapor-heated anti-inhibitor coagulant complex in hemophilia patients
.
Transfusion
. 1990;30:626–630
- . Evidence for the use of activated prothrombin complex concentrates (aPCCs) in the treatment of patients with haemophilia and inhibitors . Pathophysiol Haemost Thromb . 2002;32(suppl 1):9–12
-
.
FEIBA safety profile in multiple modes of clinical and home-therapy application
.
Haemophilia
. 2004;10(suppl 2):10–16
- . Safety of factor VIII inhibitor bypass activity (FEIBA) (10-year compilation of thrombotic adverse events) . Haemophilia . 2002;8:83–90
- . Prospective, randomised trial of two doses of rFVIIa (NovoSeven) in haemophilia patients with inhibitors undergoing surgery . Thromb Haemost . 1998;80:773–778
- Home treatment of mild to moderate bleeding episodes using recombinant factor VIIa (Novoseven) in haemophiliacs with inhibitors . Thromb Haemost . 1998;80:912–918
- . Comparative thrombotic event incidence after infusion of recombinant factor VIIa versus factor VIII inhibitor bypass activity . J Thromb Haemost . 2004;2:1700–1708
- . Immune tolerance in hemophilia with factor VIII inhibitors (Predictors of success) . Haematologica . 2001;86:1186–1193
- . The North American Immune Tolerance Registry (Practices, outcomes, outcome predictors) . Thromb Haemost . 2002;87:52–57
-
.
The role of plasma-derived factor VIII/von Willebrand factor concentrates in the treatment of hemophilia A patients
.
Haematologica
. 2003;88:21–25
- Influence of von Willebrand factor on the reactivity of human factor VIII inhibitors with factor VIII . Haemophilia . 2001;7:369–374
- . Variation in factor VIII inhibitor reactivity with different commercial factor VIII preparations (Is it of clinical importance?) . Haematologica . 2003;88:13–16
-
.
Association of anti-idiotypic antibodies with immune tolerance induction for the treatment of hemophilia A with inhibitors
.
Haematologica
. 2004;89:696–703
- . Natural autoantibodies and anti-idiotypes . Semin Thromb Hemost . 2000;26:151–155
- . Healthy subjects produce both anti-factor VIII and specific anti-idiotypic antibodies . J Clin Invest . 1994;94:1496–1505
- . Is oral tolerance therapy possible for haemophilia with inhibitors? . Vox Sang . 2001;80:61–62
- Rituximab in the treatment of acquired factor VIII inhibitors . Blood . 2002;100:3426–3428
- . Reduction of the antigenicity of factor VIII toward complex inhibitory antibody plasmas using multiply-substituted hybrid human/porcine factor VIII molecules . Blood . 2000;95:564–568
This article is based in part on the proceedings from an educational symposium held at the World Federation of Hemophilia World Congress 2004 in Bangkok, Thailand. Both the symposium and the manuscript were supported by Baxter Healthcare Corporation.
PII: S0037-1963(06)00051-5
doi: 10.1053/j.seminhematol.2006.03.005
© 2006 Elsevier Inc. All rights reserved.
« Previous
Next »
Seminars in Hematology
Volume 43
, Pages S8-S13
, April 2006
