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Seminars in Hematology
Volume 43, Issue 2
, Pages 134-143
, April 2006
Approach to the Complications of Treatment for Acute Leukemia in the Elderly
References
-
Statistics Canada: Canadian statistics: Population and demography: Population characteristics
.
Population projections for 2110, 2006, 2011, 2016, 2021, and 2026, update
. 2005;
http://www.statcan.ca. accessed July 1
-
Canadian cancer statistics. Canadian Cancer Society/National Cancer Institute of Canada
. 2005;
http://www.cancer.ca. accessed July 1
-
.
Epidemiology and hereditary aspects of acute leukemia
.
In:
Wiernik PH
, Canellos GP
, Dutcher JP
, Kyle RA
editor.
Neoplastic Disease of the Blood
. (ed 3).. New York, NY: Churchill-Livingston; 1996;p. 177
- . The relationship of patient age to the pathobiology of the clonal myeloid diseases . Semin Oncol . 2004;31:185–197
- . The treatment of acute lymphoblastic leukaemia in the elderly . Leuk Lymphoma . 2004;45:117–123
- Intensive postremission chemotherapy in adults with acute myeloid leukemia . N Engl J Med . 1994;331:896–903
- . Principal results of the Medical Research Council’s 8th acute myeloid leukaemia trial . Lancet . 1986;2:1236–1241
-
.
Acute myeloid leukemia
.
Hematology (Am Soc Hematol Educ Program)
. 2001;62–86
- . The geriatric cancer patient (Equal benefit from equal treatment) . Cancer Control . 2001;8:1–25
- . Management of hematologic malignancies in the elderly (15-year experience at the Aviano Cancer Center, Italy) . Crit Rev Oncol Hematol . 2001;39:289–305
- . Cancer burden in the aged (An epidemiologic and demographic overview) . Cancer . 1997;80:1273–1283
- . Cancer statistics, 2002 . CA Cancer J Clin . 2002;52:23–47
- . Acute myeloid leukemia in the older patient . Crit Rev Oncol Hematol . 2003;48:S17–S26
- The predictive value of hierarchical cytogenetic classification in older adults with acute myeloid leukemia (AML) (Analysis of 1065 patients entered into the United Kingdom Medical Research Council AML11 trial) . Blood . 2001;98:1312–1320
- Acute myeloid leukemia in the elderly (Assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy) . Blood . 1997;89:3323–3329
- . Improved outcome in adult acute myeloid leukemia is almost entirely restricted to young patients and associated with stem cell transplantation . Eur J Haematol . 2002;68:54–63
- . Prognostic significance of risk group stratification in elderly patients with acute myeloid leukaemia . Br J Haematol . 2001;115:25–33
- . Acute lymphoblastic leukaemia in elderly patients (Biological characteristics and therapeutic approaches) . Drugs Aging . 2004;21:779–791
- . Representation of older patients in cancer treatment trials . Cancer . 1994;74:2208–2214
- . Underrepresentation of patients 65 years of age or older in cancer-treatment trials . N Engl J Med . 1999;341:2061–2067
- . De novo acute myeloid leukaemia in patients over 55-years-old (A population-based study of incidence, treatment and outcome) . Leukemia . 1995;9:231–237
- . Management of acute myelogenous leukemia in the elderly . Cancer Control . 2003;10:469–477
- . Clinical trials and drug toxicity in the elderly . Cancer . 1983;52:1986–1992
- . Poor prognosis in elderly patients with cancer (The role of bias and undertreatment) . J Support Oncol . 2003;1:11–17
- . Multidimensional geriatric evaluation in elderly cancer patients (A practical approach) . Eur J Cancer Care (Engl) . 2004;13:424–433
- . Comorbidity (Implications for research and practice in geriatric oncology) . Crit Rev Oncol Hematol . 2003;48:239–248
- . Effect of age and comorbidity in postmenopausal breast cancer patients aged 55 years and older . JAMA . 2001;285:885–892
- Predictors of long-term outcomes in older breast cancer survivors (Perceptions versus patterns of care) . J Clin Oncol . 2003;21:855–863
- . A new method of classifying prognostic comorbidity in longitudinal studies (Development and validation) . J Chronic Dis . 1987;40:373–383
- Rating chronic medical illness burden in geropsychiatric practice and research (Application of the Cumulative Illness Rating Scale) . Psychiatry Res . 1992;41:237–248
- . Comorbidity and functional status are independent in older cancer patients . J Clin Oncol . 1998;16:1582–1587
- Supportive therapy of elderly cancer patients . Crit Rev Oncol Hematol . 2002;42:189–211
- Prognostic effect of weight loss prior to chemotherapy in cancer patients . Am J Med . 1980;69:491–497
- . Malnutrition in the institutionalized elderly (The effects on wound healing) . Ostomy Wound Manage . 2004;50:54–63
- . Nutrition and cognitive impairment in the elderly . Br J Nutr . 2001;86:313–321
- . Guidelines for the treatment of elderly cancer patients . Cancer Control . 2003;10:445–453
- . Anemia, cancer, and aging . Cancer Control . 2003;10:478–486
- . Chemotherapy of metastatic breast cancer in the elderly . JAMA . 1992;268:57–62
- . Biological interactions of aging and anemia (A focus on cytokines) . J Am Geriatr Soc . 2003;51:S18–S21
- . Emerging evidence for inflammation in conditions frequently affecting older adults (Report of a symposium) . J Am Geriatr Soc . 1999;47:1016–1025
-
.
Aging and cognition. What is normal?
.
In:
Hazzard WR
, Blass JP
, Halter JB
, Ouslander JG
, Tinetti ME
editor.
Principles of Geriatric Medicine and Gerontology
. (ed 5).. York, PA: McGraw-Hill; 2003;p. 1355–1372
- Dementia and disability (Impact on mortality) . Dement Geriatr Cogn Disord . 2003;16:7–14
- . General guidelines for the management of older patients with cancer . Oncology (Williston Park) . 2000;14:221–227
- . “Mini-Mental State.” A practical method for grading the cognitive state of patients for the clinician . J Psychiatr Res . 1975;12:189–198
- . Update on drug-related problems in the elderly . Am J Geriatr Pharmacother . 2003;1:38–43
- . Pharmacology of cancer chemotherapy in the older person . Clin Geriatr Med . 1997;13:169–183
- . Altered pharmacokinetics in the elderly . Clin Geriatr Med . 1990;6:257–267
- . Management of cancer in the older person (A practical approach) . Oncologist . 2000;5:224–237
-
.
Changes in renal function
.
In:
Hazzard WR
, Blass JP
, Halter JB
, Ouslander JG
, Tinetti ME
editor.
Principles of Geriatric Medicine and Gerontology
. (ed 5).. York, PA: McGraw-Hill; 2003;p. 543–581
- . Prediction of creatinine clearance from serum creatinine . Nephron . 1976;16:31–41
- . Estimation of creatinine clearance when urine cannot be collected . Lancet . 1971;1:975–976
- Evaluation of the Cockroft-Gault, Jelliffe and Wright formulae in estimating renal function in elderly cancer patients . Ann Oncol . 2004;15:291–295
- Therapy of untreated acute myeloid leukemia in the elderly (remission-induction using a non-cytarabine-containing regimen of mitoxantrone plus etoposide) . J Clin Oncol . 1996;14:1345–1352
- . Oral and intestinal mucositis—Causes and possible treatments . Aliment Pharmacol Ther . 2003;18:853–874
- Perspectives on cancer therapy-induced mucosal injury (Pathogenesis, measurement, epidemiology, and consequences for patients) . Cancer . 2004;100:1995–2025
- . Pathobiology of mucositis . Semin Oncol Nurs . 2004;20:11–15
- . Antineoplastic chemotherapy of the older cancer patient . Hematol Oncol Clin North Am . 2000;14:193–212
- . Clinical importance of the cytochromes P450 . Lancet . 2002;360:1155–1162
- . In vitro evaluation of cytochrome P450-mediated drug interactions between cytarabine, idarubicin, itraconazole and caspofungin . Hematology . 2004;9:217–221
- Cyclophosphamide metabolism is affected by azole antifungals . Blood . 2004;103:1557–1559
- . Reduction of polypharmacy in the elderly (A systematic review of the role of the pharmacist) . Drugs Aging . 2003;20:817–832
- Predictors of tolerance to chemotherapy in older cancer patients (A prospective pilot study) . Eur J Cancer . 2002;38:1466–1473
- . Anthracycline-induced cardiotoxicity . Ann Intern Med . 1996;125:47–58
- . Prognosis in adult acute myelogenous leukemia related to performance status and other factors . Cancer . 1976;38:329–334
- . Studies of illness in the aged. The index of ADL (A standardized measure of biological and psychological function) . JAMA . 1963;185:914–919
- . Assessment of older people (Self-maintaining and instrumental activities of daily living) . Gerontologist . 1969;9:179–186
- . Value of functional status as a predictor of mortality (Results of a prospective study) . Am J Med . 1992;93:663–669
- The Functional Assessment of Cancer Therapy scale (Development and validation of the general measure) . J Clin Oncol . 1993;11:570–579
- A global clinical measure of fitness and frailty in elderly people . CMAJ . 2005;173:489–495
- . Comprehensive geriatric assessment (a meta-analysis of controlled trials) . Lancet . 1993;342:1032–1036
- . New paradigms for treating elderly patients with cancer (The comprehensive geriatric assessment and guidelines for supportive care) . J Support Oncol . 2003;1:30–37
- . Ethnicity and prognosis in acute myeloid leukemia . Am J Hematol . 2003;72:127–134
- A simple procedure for general screening for functional disability in elderly patients . Ann Intern Med . 1990;112:699–706
- A comprehensive geriatric intervention detects multiple problems in older breast cancer patients . Crit Rev Oncol Hematol . 2004;49:69–75
- A specialized home care intervention improves survival among older post-surgical cancer patients . J Am Geriatr Soc . 2000;48:1707–1713
- . The timed “Up & Go” (A test of basic functional mobility for frail elderly persons) . J Am Geriatr Soc . 1991;39:142–148
- Development and validation of a prognostic index for 1-year mortality in older adults after hospitalization . JAMA . 2001;285:2987–2994
- . Cancer screening in elderly patients (A framework for individualized decision making) . JAMA . 2001;285:2750–2756
- . Treatment of acute myeloid leukemia with cytokines (Effect on duration of neutropenia and response to infection) . Clin Infect Dis . 1998;26:1290–1294
- A randomized placebo-controlled phase III study of granulocyte-macrophage colony-stimulating factor in adult patients (> 55 to 70 years of age) with acute myelogenous leukemia (A study of the Eastern Cooperative Oncology Group (E1490)) . Blood . 1995;86:457–462
- Recombinant human granulocyte-macrophage colony-stimulating factor after chemotherapy in patients with acute myeloid leukemia at higher age or after relapse . Blood . 1991;78:1190–1197
- A controlled study of recombinant human granulocyte colony-stimulating factor in elderly patients after treatment for acute myelogenous leukemia . N Engl J Med . 1995;332:1678–1683
-
G-CSF (lenograstim) after chemotherapy for acute myeloid leukemia
(A placebo controlled trial)
.
Blood
. 1996;88:2654a;
(suppl 1, abstr)
- . Attempts to improve treatment outcomes in acute myeloid leukemia (AML) in older patients (The results of the United Kingdom Medical Research Council AML11 trial) . Blood . 2001;98:1302–1311
- Use of glycosylated recombinant human G-CSF (lenograstim) during and/or after induction chemotherapy in patients 61 years of age and older with acute myeloid leukemia (Final results of AML-13, a randomized phase-3 study) . Blood . 2005;106:27–34
- Effect of granulocyte colony stimulating factor after intensive induction therapy in relapsed or refractory acute leukemia . N Engl J Med . 1990;323:871–877
- A double-blind controlled study of granulocyte colony-stimulating factor stared two days before induction chemotherapy in refractory acute myeloid leukemia . Blood . 1994;83:2086–2092
- Use of granulocyte colony-stimulating factor before, during, and after fludarbine plus cytarabine induction therapy of newly diagnosed acute myelogenous leukemia or myelodysplastic syndromes (Comparison with fludarabine plus cytarabine without granulocyte colony-stimulating factor) . J Clin Oncol . 1994;12:671–678
- A double-blind placebo-controlled trial of granulocyte colony-stimulating factor in elderly patients with previously untreated acute myeloid leukemia (A Southwest Oncology Group study (9031)) . Blood . 1998;91:3607–3615
- A randomized, double-blind, placebo-controlled, phase III study of filgrastim in remission induction and consolidation therapy for adults with de novo acute myeloid leukemia . Blood . 1997;90:4710–4718
- Granulocyte-macrophage colony-stimulating factor after initial chemotherapy for elderly patients with primary acute myelogenous leukemia . N Engl J Med . 1995;332:1671–1677
- Use of recombinant GM-CSF during and after remission induction chemotherapy in patients aged 61 years and older with acute myeloid leukemia (Final report of AML-11, a phase III randomized study of the Leukemia Cooperative Group of European Organisation for the Research and Treatment of Cancer and the Dutch Belgian Hemato-Oncology Cooperative Group) . Blood . 1997;90:2952–2961
- Granulocyte-macrophage colony-stimulating factor associated with induction treatment of acute myelogenous leukemia (A randomized trial by the European Organization for Research and Treatment of Cancer Leukemia Cooperative Group) . J Clin Oncol . 1996;14:2150–2159
- A placebo-controlled study of recombinant human granulocyte-macrophage colony-stimulating factor administered during and after induction treatment for de novo acute myelogenous leukemia in elderly patients . Blood . 1998;91:2722–2730
- . Hematopoietic growth factors as adjuncts to the treatment of acute myeloid leukemia . Blood . 1996;88:3675–3685
- . Use of cytokines in the treatment of acute myelocytic leukemia (A critical review) . J Clin Oncol . 1996;14:1371–1382
- Granulocyte-macrophage colony-stimulating factor to increase efficacy of mitoxantrone, etoposide and cytarabine in previously untreated elderly patients with acute myeloid leukaemia (A Swedish multicentre randomized trial) . Br J Haematol . 2004;124:474–480
-
Sequential administration of gemtuzumab ozogamicin and conventional chemotherapy as first line therapy in elderly patients with acute myeloid leukemia
(A phase II study (AML-15) of the EORTC and GIMEMA leukemia groups)
.
Haematologica
. 2004;89:950–956
- 2000 update of recommendations for the use of hematopoietic colony-stimulating factors (Evidence-based, clinical practice guidelines) . J Clin Oncol . 2000;18:3558–3585
- Economic analysis of a randomized placebo-controlled phase III study of granulocyte macrophage colony stimulating factor in adult patients (>55 to 70 years of age) with acute myelogenous leukemia . Ann Oncol . 1999;10:177–182
- . Cost effectiveness of GM-CSF in the treatment of acute myeloblastic leukemia in aged patients (protocol of GOELAM Sa3) . Therapie . 2001;56:131–133
- . Economic analysis of granulocyte colony stimulating factor as adjunct therapy for older patients with acute myelogenous leukemia (AML) (Estimates from a Southwest Oncology Group clinical trial) . Cancer Invest . 2001;19:603–610
- Clinical practice guidelines for the prevention and treatment of cancer therapy-induced oral and gastrointestinal mucositis . Cancer . 2004;100:2026–2046
- Recommended guidelines for the treatment of cancer treatment-induced diarrhea . J Clin Oncol . 2004;22:2918–2926
- Oral mucositis and the clinical and economic outcomes of hematopoietic stem-cell transplantation . J Clin Oncol . 2001;19:2201–2205
- . Cytotoxic therapy-induced D-xylose malabsorption and invasive infection during remission-induction therapy for acute myeloid leukemia in adults . J Clin Oncol . 1997;15:2254–2261
- . Prospective evaluation of gut mucosal barrier injury following various myeloablative regimens for haematopoietic stem cell transplant . Bone Marrow Transplant . 2005;35:707–711
- . Measuring mucosal damage induced by cytotoxic therapy . Support Care Cancer . 2004;12:227–233
- Palifermin for oral mucositis after intensive therapy for hematologic cancers . N Engl J Med . 2004;351:2590–2598
- Neutropenic enterocolitis in adults (Systematic analysis of evidence quality) . Eur J Haematol . 2005;75:1–13
-
.
Symptom management in the elderly cancer patient
(Fatigue, pain, and depression)
.
J Natl Cancer Inst Monogr
. 2004;32:150–157
-
.
Pain management
.
In:
Hazzard WR
, Blass JP
, Halter JB
, Ouslander JG
, Tinetti ME
editor.
Principles of Geriatric Medicine and Gerontology
. (ed 5).. York, PA: McGraw-Hill; 2003;p. 303–321
-
.
Delirium
.
In:
Hazzard WR
, Blass JP
, Halter JB
, Ouslander JG
, Tinetti ME
editor.
Principles of Geriatric Medicine and Gerontology
. (ed 5).. York, PA: McGraw-Hill; 2003;p. 1503–1516
-
.
Infectious complications in patients receiving cytotoxic therapy for acute leukemia
(History, background and approaches to management)
.
In:
Wingard JR
, Bowden RA
editor.
Management of Infection in Oncology Patients
. London, UK: Martin Dunitz; 2003;p. 71–104
- Elderly haematological patients with chemotherapy-induced febrile neutropenia have similar rates of infection and outcome to younger adults (A prospective study of risk-adapted therapy) . Br J Haematol . 2003;120:209–216
- . Economic issues (Toward a cost-effective approach to the management of febrile neutropenia in Japan) . Clin Infect Dis . 2004;39(suppl 1):S68–S69
- . Antimicrobial prophylaxis in febrile neutropenia . Clin Infect Dis . 2004;39(suppl 1):S65–S67
- Prophylaxis with fluoroquinolones for bacterial infections in neutropenic patients (A meta-analysis) . Clin Infect Dis . 1996;23:795–805
- . Reappraisal with meta-analysis of the addition of gram-positive prophylaxis to fluoroquinolone in neutropenic patients . J Clin Oncol . 2003;21:4127–4137
-
.
Fluoroquinolone prophylaxis for profoundly neutropenic cancer patients
(A meta-analysis)
.
Curr Oncol
. 1997;4(suppl 2):S2–S7
- . Efficacy of quinolone prophylaxis in neutropenic cancer patients (A meta-analysis) . J Clin Oncol . 1998;16:1179–1187
-
.
Meta-analysis
(Antibiotic prophylaxis reduces mortality in neutropenic patients)
.
Ann Intern Med
. 2005;142:979–995
-
.
Point
(Fluoroquinolone-based antibacterial chemoprophylaxis in neutropenic cancer patients works for defined populations, but must be used wisely)
.
J Natl Compr Cancer Network
. 2004;2:433–444
-
.
Counterpoint
(Routine anti-bacterial prophylaxis is not indicated in neutropenic patients with hematological maligancies)
.
J Natl Compr Cancer Network
. 2004;2:445–451
- . Relationship between quinolone use and emergence of ciprofloxacin-resistant Escherichia coli in bloodstream infections . Antimicrob Agents Chemother . 1995;39:520–524
- Incidence and clinical impact of fluoroquinolone-resistant Escherichia coli in the faecal flora of cancer patients treated with high dose chemotherapy and ciprofloxacin prophylaxis . J Antimicrob Chemother . 1999;44:117–120
- Ciprofloxacin prophylaxis in patients with acute leukemia and granulocytopenia in an area with a high prevalence of ciprofloxacin-resistant Escherichia coli . Cancer . 2003;97:419–424
- . Bacteremia due to viridans streptococcus in neutropenic patients with cancer (Clinical spectrum and risk factors) . Clin Infect Dis . 1994;18:25–31
- Factors associated with bacteremia in febrile, granulocytopenic cancer patients . Eur J Cancer . 1994;30A:430–437
- . Outcomes of bacteremia in patients with cancer and neutropenia (Observations from two decades of epidemiological and clinical trials) . Clin Infect Dis . 1997;25:247–259
- . Septicemia and shock syndrome due to viridans streptococci (A case-control study of predisposing factors) . Clin Infect Dis . 1992;14:1201–1207
- . Meta-analysis of prophylactic or empirical antifungal treatment versus placebo or no treatment in patients with cancer complicated by neutropenia . BMJ . 1997;314:1238–1244
- Prophylactic action of oral fluconazole against infection in neutropenic patients—A meta-analysis of 16 randomized, controlled trials . Cancer . 2000;89:1611–1625
- . Antifungal prophylaxis for severely neutropenic chemotherapy recipients (A meta analysis of randomized-controlled clinical trials) . Cancer . 2002;94:3230–3246
- Itraconazole prevents invasive fungal infections in neutropenic patients treated for hematologic malignancies (Evidence from a meta-analysis of 3,597 patients) . J Clin Oncol . 2003;21:4615–4626
- . Evidence-based assessment of primary antifungal prophylaxis in patients with hematologic malignancies . Blood . 2003;101:3365–3372
- Itraconazole versus fluconazole for prevention of fungal infections in patients receiving allogeneic stem cell transplants . Blood . 2004;103:1527–1533
- . Randomized placebo-controlled trial of fluconazole prophylaxis for neutropenic cancer patients (Benefit based on purpose and intensity of cytotoxic therapy) . Clin Infect Dis . 1999;28:331–340
- 2002 guidelines for the use of antimicrobial agents in neutropenic patients with cancer . Clin Infect Dis . 2002;34:730–751
- Antimicrobial therapy of unexplained fever in neutropenic patients—Guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO), Study Group Interventional Therapy of Unexplained Fever, Arbeitsgemeinschaft Supportivmassnahmen in der Onkologie (ASO) of the Deutsche Krebsgesellschaft (DKG-German Cancer Society) . Ann Hematol . 2003;82(suppl 2):S105–S117
-
Fever and neutropenia
.
J Natl Comp Cancer Network
. 2004;2:390–432
- . Febrile neutropenia—Guideline in Japan . Gan To Kagaku Ryoho . 2000;27:161–165
- . New oral drugs in older patients (A review of idarubicin in elderly patients) . Crit Rev Oncol Hematol . 2004;49:153–163
- . Evidence-based recommendations for antimicrobial use in febrile neutropenia in Japan (Executive summary) . Clin Infect Dis . 2004;39(suppl 1):S49–S52
- Clinical guide for the evaluation and treatment of patients with neutropenia and fever . Rev Esp Quimioter . 2001;14:75–83
- The Multinational Association for Supportive Care in Cancer risk index (A multinational scoring system for identifying low-risk febrile neutropenic cancer patients) . J Clin Oncol . 2000;18:3038–3051
- . Beta lactam monotherapy versus beta lactam-aminoglycoside combination therapy for fever with neutropenia (Systematic review and meta-analysis) . BMJ . 2003;326:1111–1120
- . Monotherapy or aminoglycoside-containing combinations for empirical antibiotic treatment of febrile neutropenic patients (a meta-analysis) . Lancet Infect Dis . 2002;2:231–242
- . Management of infection in cancer patients. studies of the EORTC International Antimicrobial Therapy Group (IATG) . Eur J Cancer . 2002;38(suppl 4):S82–S87
- . Vancomycin does not benefit persistently febrile neutropenic people with cancer . Cancer Treat Rev . 2004;30:119–126
-
.
Efficacy of piperacillin/tazobactam as initial empiric therapy for febrile neutropenia in patients with hematological malignancy
.
Blood
. 2003;102:281a;
(abstr 1000)
-
.
In:
A systematic review of the efficacy of azoles and lipid-based formulations of amphotericin B as empirical anti-fungal therapy in persistently febrile neutropenic patients despite broad-spectrum anti-bacterial therapy
. Toronto, Canada: 40th Interscience Conference on Antimicrobial Agents and Chemotherapy; 2000;p. 364;
September 17-20, (abstr 702)
- Liposomal amphotericin B for empirical therapy in patients with persistent fever and neutropenia . N Engl J Med . 1999;340:764–771
- A systematic review of the antifungal effectiveness and tolerability of amphotericin B formulations . Clin Ther . 2003;25:1295–1320
- Intravenous and oral itraconazole versus intravenous amphotericin B deoxycholate as empirical antifungal therapy for persistent fever in neutropenic patients with cancer who are receiving broad-spectrum antibacterial therapy. A randomized, controlled trial . Ann Intern Med . 2001;135:412–422
- Voriconazole compared with liposomal amphotericin B for empirical antifungal therapy in patients with neutropenia and persistent fever . N Engl J Med . 2002;346:225–234
- Caspofungin versus liposomal amphotericin B for empirical antifungal therapy in patients with persistent fever and neutropenia . N Engl J Med . 2004;351:1391–1402
- Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants (An international consensus) . Clin Infect Dis . 2002;34:7–14
- Invasive fungal infections after allogeneic peripheral blood stem cell transplantation (Incidence and risk factors in 395 patients) . Br J Haematol . 2002;116:475–482
- Guidelines for the management of intravascular catheter-related infections . Clin Infect Dis . 2001;32:1249–1272
- Deterioration of previous acute lung injury during neutropenia recovery . Crit Care Med . 2002;30:781–786
- . Perirectal infections in acute leukemia—Improved survival after incision and debridement . Ann Intern Med . 1984;100:515–518
- Pulmonary infiltrates in febrile patients with neutropenia. Risk factors and outcome under empirical antimicrobial therapy in a randomized multicenter study . Cancer . 1994;73:2296–2304
- . Neutropenic enterocolitis (Spectrum of the disease and comparison of definite and possible cases) . Clin Infect Dis . 1998;27:695–699
PII: S0037-1963(06)00018-7
doi: 10.1053/j.seminhematol.2006.01.001
© 2006 Elsevier Inc. All rights reserved.
« Previous
Seminars in Hematology
Volume 43, Issue 2
, Pages 134-143
, April 2006
