Seminars in Hematology
Volume 42, Issue 2 , Pages 85-90 , April 2005

Human leukocyte antigen matching in cord blood transplantation

  • Eliane Gluckman

      Affiliations

    • Department of Hematologie Bone Marrow Transplant, Eurocord, Institute of Hematology, APHP Hospital Saint Louis, Paris, France
    • Corresponding Author InformationAddress correspondence to Eliane Gluckman, MD, FRCP, Hospital Saint Louis, 1 Ave Claude Vellefaux, 75475 Paris Cedex 10, France
    • ,
  • Gesine Koegler

      Affiliations

    • José Carreras Eurocord/Netcord Bank Germany at the Institute for Transplantation Diagnostics and Cell Therapeutics, University of Düsseldorf Medical School, Düsseldorf, Germany
    • ,
  • Vanderson Rocha

      Affiliations

    • Department of Hematologie Bone Marrow Transplant, Eurocord, Institute of Hematology, APHP Hospital Saint Louis, Paris, France

References 

  1. Gluckman E , Broxmeyer HE , Auerbach AD , et al.   Hematopoietic reconstitution in a patient with Fanconi’s anemia by means of umbilical-cord blood from an HLA-identical sibling . N Engl J Med . 1989;321:1174–1178
  2. Grewal SS , Barker JN , Davies S , Wagner JE . Unrelated donor hematopoietic cell transplantation (Marrow or umbilical cord blood?) . Blood . 2003;101:4233–4244
  3. Barker JN , Krepski TP , DeFor T , Davies JM , Wagner JE , Weisdorf DJ , et al.   Searching for unrelated donor hematopoietic stem cell grafts (Availability and speed of umbilical cord blood versus bone marrow) . Biol Blood Marrow Transplant . 2002;8:257–260
  4. Dalle JH , Duval M , Moghrabi A , Wagner E , Vachon MF , Barrette S , et al.   Results of an unrelated transplant search strategy using partially HLA-mismatched cord blood as an immediate alternative to HLA-matched bone marrow . Bone Marrow Transplant . 2004;33:605–611
  5. Gluckman E , Rocha V , Arcese W , Michel G , Sanz G , Chan KW , et al.   Factors associated with outcomes of unrelated cord blood transplant (guidelines for donor choice) . Exp Hematol . 2004;32:397–407
  6. Rubinstein P , Carrier C , Scaradavou A , Kurtzberg J , Adamson J , Migliaccio AR , et al.   Outcomes among 562 recipients of placental-blood transplants from unrelated donors . N Engl J Med . 1998;339:1565–1577
  7. Wagner JE , Barker JN , DeFor TE , Baker KS , Blazar BR , Eide C , et al.   Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases (Influence of CD34 cell dose and HLA disparity on treatment-related mortality and survival) . Blood . 2002;100:1611–1618
  8. Rocha V , Wagner JE , Sobocinski KA , et al.   Graft-versus-host disease in children who have received a cord blood or bone marrow transplant from an HLA-identical sibling . N Engl J Med . 2000;342:1846–1854
  9. Rocha V, Cornish J, Sievers E, Klein JP, Zhang JJ, Horowitz MM, et al  Comparison of outcomes of unrelated bone marrow and umbilical cord blood transplants in children with acute leukemia . Blood . 2001;97:2962–2971
  10. Rocha V , Labopin M , Sanz G , Filipovich A , Locatelli F , Peters C , et al.   Outcomes after transplants of umbilical cord blood or bone marrow from unrelated donors in adults with acute leukemia . N Engl J Med . 2004;351:12–21
  11. Laughlin MJ, Eapen M, Rubinstein P, Wagner JE, Zhang MJ, Champlin RE, et al  Outcomes after transplantation of cord blood or bone marrow from unrelated donors in adults with leukemia . N Engl J Med . 2004;35:2265–2275
  12. Barker JN , Davies SM , DeFor T , Ramsay NK , Weisdorf DJ , Wagner JE . Survival after transplantation of unrelated donor umbilical cord blood is comparable to that of human leukocyte antigen-matched unrelated donor bone marrow (Results of a matched-pair analysis) . Blood . 2001;97:2957–2961
  13. Kogler G , Enczmann J , Rocha V , Gluckman E , Wernet P . High resolution HLA typing by sequencing for HLA-A, B, C, Dr, DQ in 115 unrelated cord blood patient pairs (Does it improve outcomes after cord blood transplantation?) . Blood . 2004;104:279a; (abstr 973)
  14. Petersdorf EW , Anasetti C , Martin PJ , Gooley T , Radich J , Malkki M , et al.   Limits of HLA mismatching in unrelated hematopoietic cell transplantation . Blood . 2004;104:2976–2980
  15. Kogler G , Midlleton PG , Wilke M , Rocha V , Esendam B , Enczmann J , et al.   Recipient cytokines for TNF-α and IL-10 and the minor histocompatibility antigens HY and CD31 codon 125 are not associated with occurrence or severity of acute GVHD in unrelated cord blood transplantation (A retrospective analysis) . Transplantation . 2002;74:1167–1175
  16. Michel G , Rocha V , Chevret S , Arcese W , Chan K-W , Filipovich A , et al.   Unrelated cord blood transplantation for childhood acute myeloid leukemia (A Eurocord group analysis) . Blood . 2003;102:1–8
  17. Sanz MA . Cord blood transplantation in patients with leukemia—A real alternative for adults . N Engl J Med . 2004;351:2328–2330
  18. Laughlin MJ , Baker J , Bambach B , Koc ON , Rizzieri DA , Wagner JE . Hematopoietic engraftment and survival in adult recipients of umbilical cord blood from unrelated donors . N Engl J Med . 2001;344:1815–1822
  19. Sanz GF , Saavedra S , Planelles D , Senent L , Cervera J , Barragan E , et al.   Standardized, unrelated donor cord blood transplantation in adults with hematological malignancies . Blood . 2001;98:2332–2338
  20. Ooi J , Iseki T , Takahashi S , Tomonari A , Takasugi K , Shimohakamada Y , et al.   Unrelated cord blood transplantation for adult patients with de novo acute myeloid leukemia . Blood . 2004;103:489–491
  21. Ooi J , Iseki T , Takahashi S , Tomonari A , Ishii K , Takasugi K , et al.   Unrelated cord blood transplantation for adult patients with advanced myelodysplastic syndrome . Blood . 2003;101:4711–4713
  22. Barker JN , Weisdorf DJ , DeFor TE , Blazar BR , Miller JS , Wagner JE , et al.   Rapid and complete donor chimerism in adult recipients of unrelated donor umbilical cord blood transplantation after reduced-intensity conditioning . Blood . 2003;102:1915–1919
  23. Koh LP , Chao NJ . Umbilical cord blood transplantation in adults using myeloablative and nonmyeloablative preparative regimens . Biol Blood Marrow Transplant . 2004;10:1–22
  24. Steinbrook R . The cord blood bank controversies . N Engl J Med . 2004;351:2255–2257

 Supported by Eurocord II and Eurocord III grants from FP5 QLRT-1999-00380 and QLRT-2001-01918 and PHRC AOM 96171.

PII: S0037-1963(05)00008-9

doi: 10.1053/j.seminhematol.2005.01.006

Seminars in Hematology
Volume 42, Issue 2 , Pages 85-90 , April 2005

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