« Previous
Next »
Seminars in Hematology
Volume 42, Issue 1
, Pages 56-62
, January 2005
Interplay between ADAMTS13 and von Willebrand factor in inherited and acquired thrombotic microangiopathies
References
- . Thrombotic microangiopathies . N Engl J Med . 2002;347:589–600
-
.
Hyalin thrombosis of the terminal arterioles and capillaries
(A hitherto undescribed disease)
.
Proc N Y Pathol Soc
. 1924;24:21–24
- . Hämolytisch-urämische Syndrome (bilaterale Nierenrindennekrosen bei akuten erworbenen hämolytischen Anämien) . Schweiz Med Wochenschr . 1955;85:905–909
- Unusually large plasma factor VIII:von Willebrand factor multimers in chronic relapsing thrombotic thrombocytopenic purpura . N Engl J Med . 1982;307:1432–1435
- . Partial purification and characterization of a protease from human plasma cleaving von Willebrand factor to fragments produced by in vivo proteolysis . Blood . 1996;87:4223–4234
- . Physiologic cleavage of von Willebrand factor by a plasma protease is dependent on its conformation and requires calcium ion . Blood . 1996;87:4235–4244
- . Deficient activity of von Willebrand factor-cleaving protease in chronic relapsing thrombotic thrombocytopenic purpura . Blood . 1997;89:3097–3103
- von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome . N Engl J Med . 1998;339:1578–1584
- . Acquired deficiency of von Willebrand factor-cleaving protease in a patient with thrombotic thrombocytopenic purpura . Blood . 1998;91:2839–2846
- . Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura . N Engl J Med . 1998;339:1585–1594
- . The Japanese experience with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome . Semin Hematol . 2004;41:68–74
- . Deficient activity of von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura . Expert Rev Cardiovasc Ther . 2003;1:243–255
-
.
Platelets
(Thrombotic thrombocytopenic purpura)
.
Hematology (Am Soc Hematol Educ Program)
. 2002;9:315–334
- Upshaw-Schulman syndrome revisited (A concept of congenital thrombotic thrombocytopenic purpura) . Int J Hematol . 2001;74:101–108
- . The genetics and pathogenesis of haemolytic uraemic syndrome and thrombotic thrombocytopenic purpura . Curr Opin Nephrol Hypertens . 2002;11:431–435
- . Genetic screening in haemolytic uraemic syndrome . Curr Opin Nephrol Hypertens . 2003;12:653–657
-
.
Thrombotic microangiopathies in bone marrow and organ transplant patients
.
J Clin Apheresis
. 2002;17:118–123
- . The association of pregnancy with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome . Curr Opin Hematol . 2003;10:339–344
- . Thrombotic microangiopathy in renal transplantation . Ann Transplant . 2002;7:28–33
- . VWF73, a region from D1596 to R1668 of von Willebrand factor, provides a minimal substrate for ADAMTS-13 . Blood . 2004;103:607–612
- . ADAMTS-13 activity in plasma is rapidly measured by a new ELISA method that uses recombinant VWF-A2 domain as substrate . J Thromb Haemost . 2004;2:485–491
- . An enzyme immunoassay of ADAMTS13 distinguishes patients with thrombotic thrombocytopenic purpura from normal individuals and carriers of ADAMTS13 mutations . Thromb Haemost . 2004;91:806–811
- Nonneutralizing IgM and IgG antibodies to von Willebrand factor-cleaving protease (ADAMTS-13) in a patient with thrombotic thrombocytopenic purpura . Blood . 2003;102:3241–3243
- . Effect of plasma exchange on plasma ADAMTS13 metalloprotease activity, inhibitor level, and clinical outcome in patients with idiopathic and nonidiopathic thrombotic thrombocytopenic purpura . Blood . 2004;103:4043–4049
- . Immunologic differentiation of classic hemophilia (factor VIII deficiency) and von Willebrand’s disease, with observations on combined deficiencies of antihemophilic factor and proaccelerin (factor V) and on an acquired circulating anticoagulant against antihemophilic factor . J Clin Invest . 1971;50:244–254
- . von Willebrand disease . Hum Pathol . 1987;18:140–152
- . Biochemistry and genetics of von Willebrand factor . Annu Rev Biochem . 1998;67:395–424
- . Von Willebrand factor, platelets and endothelial cell interactions . J Thromb Haemost . 2003;1:1335–1342
- . Synthesis of von Willebrand factor by cultured human endothelial cells . Proc Natl Acad Sci U S A . 1974;71:1906–1909
- . Synthesis of factor VIII antigen by cultured guinea pig megakaryocytes . J Clin Invest . 1977;60:914–921
- . Adhesion of platelets to human artery subendothelium (Effect of factor VIII-von Willebrand factor of various multimeric composition) . Blood . 1984;63:128–139
- . Inducible secretion of large, biologically potent von Willebrand factor multimers . Cell . 1986;46:185–190
- . von Willebrand factor released from Weibel-Palade bodies binds more avidly to extracellular matrix than that secreted constitutively . Blood . 1987;69:1531–1534
- . Shear-dependent changes in the three-dimensional structure of human von Willebrand factor . Blood . 1996;88:2939–2950
- Platelet shape changes and adhesion under high shear flow . Arterioscler Thromb Vasc Biol . 2002;22:329–334
- . Identification of a cleavage site directing the immunochemical detection of molecular abnormalities in type IIA von Willebrand factor . Proc Natl Acad Sci U S A . 1990;87:6306–6310
- Quantitative analysis of von Willebrand factor propeptide release in vivo (Effect of experimental endotoxemia and administration of 1-deamino-8-D-arginine vasopressin in humans) . Blood . 1996;88:2951–2958
- . Partial amino acid sequence of purified von Willebrand factor-cleaving protease . Blood . 2001;98:1654–1661
- . Purification of human von Willebrand factor-cleaving protease and its identification as a new member of the metalloproteinase family . Blood . 2001;98:1662–1666
- A novel human metalloprotease synthesized in the liver and secreted into the blood (Possibly, the von Willebrand factor-cleaving protease?) . J Biochem . 2001;130:475–480
- . Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura . J Biol Chem . 2001;276:41059–41063
- . Molecular cloning of a gene encoding a new type of metalloproteinase-disintegrin family protein with thrombospondin motifs as an inflammation associated gene . J Biol Chem . 1997;272:556–562
- . ADAMTS (A novel family of extracellular matrix proteases) . Int J Biochem Cell Biol . 2001;33:33–44
- Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura . Nature . 2001;413:488–494
- . The CUB domain. A widespread module in developmentally regulated proteins . J Mol Biol . 1993;231:539–545
- . Arg-Gly-Asp (A versatile cell recognition signal) . Cell . 1986;44:517–518
- . Processing of von Willebrand factor by ADAMTS-13 . Biochemistry . 2002;41:11065–11070
- . ADAMTS13 and TTP . Curr Opin Hematol . 2002;9:389–394
- . Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains . Gene . 2002;283:49–62
- Mutations and common polymorphisms in ADAMTS13 gene responsible for von Willebrand factor-cleaving protease activity . Proc Natl Acad Sci U S A . 2002;99:11902–11907
- Cloning, expression, and functional characterization of the von Willebrand factor-cleaving protease (ADAMTS13) . Blood . 2002;100:3626–3632
- . Cleavage of von Willebrand factor requires the spacer domain of the metalloprotease ADAMTS13 . J Biol Chem . 2003;278:30136–30141
- . Recovery and half-life of von Willebrand factor-cleaving protease after plasma therapy in patients with thrombotic thrombocytopenic purpura . Thromb Haemost . 1999;81:8–13
- ADAMTS-13 cysteine-rich/spacer domains are functionally essential for von Willebrand factor cleavage . Blood . 2003;102:3232–3237
- . Identification of strain-specific variants of mouse Adamts13 gene encoding von Willebrand factor-cleaving protease . J Biol Chem . 2004;279:30896–30903
- . Cleavage of the ADAMTS13 propeptide is not required for protease activity . J Biol Chem . 2003;278:46643–46648
- Detection of von Willebrand factor-cleaving protease (ADAMTS-13) in human platelets . Biochem Biophys Res Commun . 2004;313:212–216
- von Willebrand factor cleaving protease and ADAMTS13 mutations in childhood TTP . Blood . 2003;101:1845–1850
- ADAMTS13 gene defects in two brothers with constitutional thrombotic thrombocytopenic purpura and normalization of von Willebrand factor-cleaving protease activity by recombinant human ADAMTS13 . Br J Haematol . 2003;120:821–824
- Mutation analysis and clinical implications of von Willebrand factor-cleaving protease deficiency . Kidney Int . 2003;63:1995–1999
- . ADAMTS13 gene mutation in congenital thrombotic thrombocytopenic purpura with previously reported normal VWF cleaving protease activity . Blood . 2003;101:4449–4451
- Molecular characterization of ADAMTS13 gene mutations in Japanese patients with Upshaw-Schulman syndrome . Blood . 2004;103:1305–1310
- . Severe ADAMTS-13 deficiency in childhood . Semin Hematol . 2004;41:83–89
- . Congenital thrombotic thrombocytopenic purpura in association with a mutation in the second CUB domain of ADAMTS13 . Blood . 2004;103:627–629
- Ten candidate ADAMTS13 mutations in six French families with congenital thrombotic thrombocytopenic purpura (Upshaw-Schulman syndrome) . J Thromb Haemost . 2004;2:424–429
- Identification of novel mutations in ADAMTS13 in an adult patient with congenital thrombotic thrombocytopenic purpura . Blood . 2004;104:2081–2083
- Epitope mapping of ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura . Blood . 2004;103:4514–4519
- ADAMTS-13 metalloprotease interacts with the endothelial cell-derived ultra-large von Willebrand factor . J Biol Chem . 2003;278:29633–29639
- ADAMTS-13 rapidly cleaves newly secreted ultralarge von Willebrand factor multimers on the endothelial surface under flowing conditions . Blood . 2002;100:4033–4039
- P-selectin anchors newly released ultralarge von Willebrand factor multimers to the endothelial cell surface . Blood . 2004;103:2150–2156
- . Regulated secretion in endothelial cells (Biology and clinical implications) . Thromb Haemost . 2001;86:1148–1155
- . Changes in health and disease of the metalloprotease that cleaves von Willebrand factor . Blood . 2001;98:2730–2735
- . Changes in von Willebrand factor-cleaving protease (ADAMTS13) activity after infusion of desmopressin . Blood . 2003;101:946–948
- . Decreased von Willebrand factor protease activity associated with thrombocytopenic disorders . Blood . 2001;98:1842–1846
- . Von Willebrand factor-cleaving protease (ADAMTS13) in thrombocytopenic disorders (A severely deficient activity is specific for thrombotic thrombocytopenic purpura) . Blood . 2002;100:710–713
- . Advances in the pathogenesis, diagnosis, and treatment of thrombotic thrombocytopenic purpura . J Am Soc Nephrol . 2003;14:1072–1081
- . Binding of platelet glycoprotein Ibalpha to von Willebrand factor domain A1 stimulates the cleavage of the adjacent domain A2 by ADAMTS13 . Proc Natl Acad Sci U S A . 2004;101:10578–10583
-
Crawley JT, Lam JK, Rance JB, Mollica LR, O’Donnell JS, Lane DA: Proteolytic inactivation of ADAMTS13 by thrombin and plasmin. Blood (in press)
- . Control of von Willebrand factor multimer size by thrombospondin-1 . J Exp Med . 2001;193:1341–1349
- Role of thrombospondin-1 in control of von Willebrand factor multimer size in mice . J Biol Chem . 2004;279:21439–21448
PII: S0037-1963(04)00213-6
doi: 10.1053/j.seminhematol.2004.09.008
© 2005 Elsevier Inc. All rights reserved.
« Previous
Next »
Seminars in Hematology
Volume 42, Issue 1
, Pages 56-62
, January 2005
